3D game engine/framework in C, with Luajit and Python bindings now
Ct.js is a desktop game engine that makes learning programming fun
Pycraft is an open-source, OpenGL based game made in Python
Orx: Portable Game Engine
Tools and Z80 engine for creating adventure games. (RUST)
Vivid3D is an open-source 3D engine with powerful 2D UI.
scriptable game engine with built-in support for 2D graphics and sound