Best Standard Operating Procedure (SOP) Software

Compare the Top Standard Operating Procedure (SOP) Software as of November 2025

What is Standard Operating Procedure (SOP) Software?

Standard operating procedure (SOP) software allows companies to optimize their efficiency through the management of documents, employee training, and regulation compliance. Compare and read user reviews of the best Standard Operating Procedure (SOP) software currently available using the table below. This list is updated regularly.

  • 1
    Process Street

    Process Street

    Process Street

    Process Street is an AI-powered compliance operations platform that automates complex workflows, enforces standards, and tracks audit data in real time. Teams use it to create structured SOPs, assign tasks, collect data, and monitor execution with intelligent oversight. From onboarding and audits to vendor management and document control, Process Street ensures every step is followed and every action is logged. Built for regulated industries like financial services, healthcare, and manufacturing, it supports frameworks such as ISO, SOC 2, SOX, and HIPAA. With role-based permissions, audit logs, and powerful integrations, Process Street replaces static documents, spreadsheets, and manual processes with a single automated system of record. Use AI to streamline approvals, catch risks early, and generate audit-ready evidence. Trusted by teams at Cargill, DoorDash, Farmers Insurance, and Hartford Healthcare.
    Starting Price: $1500/month
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  • 2
    Epsilon3

    Epsilon3

    Epsilon3

    Epsilon3 is an AI-powered procedure and resource management tool designed for teams building, testing, and operating advanced products and systems. ✔ Standardize & Optimize Processes Our interoperable procedure execution system replaces inefficient checklists managed with paper, spreadsheets, docs, and outdated planning tools. Automatically track every step to ensure quality, consistency, and traceability. ✔ Fuel Rapid Iteration & Innovation Built-in version control, conditional workflows, and real-time data synchronization keep teams on the same page. Enable continuous improvement and quick, data-driven decisions to stay far ahead of the competition. ✔ Streamline & Scale Operations Securely integrate siloed systems and automate error-prone tasks to boost productivity and prevent delays. Simplify training, reduce costs, and maintain efficiency as your operations expand to meet demand. Trusted by industry leaders like NASA, Firefly Aerospace, and Commonwealth Fusion.
    Starting Price: $100/user/month
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  • 3
    Interfacing Enterprise Process Center (EPC)

    Interfacing Enterprise Process Center (EPC)

    Interfacing Technologies Corporation

    Interfacing’s Enterprise Process Center (EPC) is an AI-powered Integrated Management System that unifies BPM, QMS, Document Control, and GRC into one platform. Organizations use EPC to model and automate processes, control documents, manage risks, and maintain regulatory compliance with full traceability and audit readiness. Built for highly regulated sectors such as aerospace, life sciences, finance, and government, EPC provides real-time visibility, automated workflows, and AI-driven insights that improve quality and reduce operational risk. The platform is ISO 27001 certified and fully validated for 21 CFR Part 11, making it suitable for mission-critical environments requiring strong governance, security, and control. EPC also includes low-code automation, process mining, audit management, training tracking, CAPA workflows, and dashboards to help teams streamline operations and continuously improve. AI strengthens governance, improves accuracy, and reinforces regulatory control.
    Starting Price: $10/month/user
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  • 4
    MaintainX

    MaintainX

    MaintainX

    MaintainX is the world-leading mobile-first workflow management platform for industrial and frontline workers. We are a modern IoT-enabled cloud-based tool for maintenance, safety, and operations on equipment and facilities. MaintainX helps businesses track reactive and preventive maintenance, and control daily operations, such as safety inspections, quality inspections, and operating checklists—all with a digital audit trail. Here's what we digitize and take away from the clipboard: - Safety Procedures - Environmental Checklists - Tooling & Gauge Reporting - Maintenance Procedures - Auditing/Inspection Workflows - Training Checklists We allow plant managers to become more efficient operators by delivering real-time business insights from the field. MaintainX is designed to work with organizations of all sizes - whether you're running a small team of 2 or coordinating a massive team of thousands of folks around multiple locations.
    Starting Price: $0/month/user
  • 5
    Methodologee

    Methodologee

    Methodologee

    Get things done faster without missing a beat. Securely manage and share your procedures and files from one place—anywhere, anytime, and from any device. Methodologee helps keep you organized so you can pull up procedures in a snap. Its consistent format makes it so easy to create and follow a process, you’ll even enjoy it. Give your dream team what they need to get the job done right, every time. You can have them create procedures and use comments for productive collaboration. Methodologee protects your data for your peace of mind. You also have full control over what each user can see and do in your account. We're on a mission to bring Franchisor Operation's Manuals to life and transform them into what they're meant to be, the #1 place franchisees go to successfully run and grow their business. Find freedom in your business and focus on what you love.
    Starting Price: $7 per month
  • 6
    Flowster

    Flowster

    Flowster

    Flowster was created so that entrepreneurs like you, who aren’t business process experts, can easily create highly detailed Standard Operating Procedures (SOPs) that will allow you to make more while working less in your business! SOPs guide your team members through every step of your repetitive processes so that they don't have to rely on memory alone and make mistakes that will cost you money! Create your SOPs ultra-fast by choosing from our ever-expanding library of fully customizable SOP templates, or start from scratch by creating your SOPs "on-the-fly" with our Flowster Capture chrome extension. When you have well-defined business processes in place, you can easily delegate work to your (remote) team so that you can work fewer hours and spend more time with the ones you love. When it comes to getting more done, there is nothing better than having a proven process to show you the exact steps you need to take.
    Starting Price: $12 per month
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