Python Agentic AI Tools

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Browse free open source Python Agentic AI Tools and projects below. Use the toggles on the left to filter open source Python Agentic AI Tools by OS, license, language, programming language, and project status.

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  • 1
    AutoGPT

    AutoGPT

    Powerful tool that lets you create and run intelligent agents

    AutoGPT is an experimental open-source application showcasing the capabilities of the GPT-4 language model. This program, driven by GPT-4, chains together LLM "thoughts", to autonomously achieve whatever goal you set. As one of the first examples of GPT-4 running fully autonomously, AutoGPT pushes the boundaries of what is possible with AI.
    Downloads: 22 This Week
    Last Update:
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  • 2
    OpenAI Python

    OpenAI Python

    The official Python library for the OpenAI API

    The OpenAI Python library provides convenient access to the OpenAI REST API from any Python 3.7+ application. The library includes type definitions for all request params and response fields, and offers both synchronous and asynchronous clients powered by httpx.
    Downloads: 17 This Week
    Last Update:
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  • 3
    CAMEL AI

    CAMEL AI

    Finding the Scaling Law of Agents. A multi-agent framework

    The rapid advancement of conversational and chat-based language models has led to remarkable progress in complex task-solving. However, their success heavily relies on human input to guide the conversation, which can be challenging and time-consuming. This paper explores the potential of building scalable techniques to facilitate autonomous cooperation among communicative agents and provide insight into their "cognitive" processes. To address the challenges of achieving autonomous cooperation, we propose a novel communicative agent framework named role-playing. Our approach involves using inception prompting to guide chat agents toward task completion while maintaining consistency with human intentions. We showcase how role-playing can be used to generate conversational data for studying the behaviors and capabilities of chat agents, providing a valuable resource for investigating conversational language models.
    Downloads: 13 This Week
    Last Update:
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  • 4
    Agent Zero

    Agent Zero

    Agent Zero AI framework

    Agent Zero is not a predefined agentic framework. It is designed to be dynamic, organically growing, and learning as you use it. Agent Zero is fully transparent, readable, comprehensible, customizable and interactive. Agent Zero uses the computer as a tool to accomplish its (your) tasks. Agents can communicate with their superiors and subordinates, asking questions, giving instructions, and providing guidance. Instruct your agents in the system prompt on how to communicate effectively. The terminal interface is real-time streamed and interactive. You can stop and intervene at any point. If you see your agent heading in the wrong direction, just stop and tell it right away. There is a lot of freedom in this framework. You can instruct your agents to regularly report back to superiors asking for permission to continue. You can instruct them to use point-scoring systems when deciding when to delegate subtasks. Superiors can double-check subordinates' results and disputes.
    Downloads: 12 This Week
    Last Update:
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  • 5
    Self-Operating Computer

    Self-Operating Computer

    A framework to enable multimodal models to operate a computer

    The Self-Operating Computer Framework is an innovative system that enables multimodal models to autonomously operate a computer by interpreting the screen and executing mouse and keyboard actions to achieve specified objectives. This framework is compatible with various multimodal models and currently integrates with GPT-4o, o1, Gemini Pro Vision, Claude 3, and LLaVa. Notably, it was the first known project to implement a multimodal model capable of viewing and controlling a computer screen. The framework supports features like Optical Character Recognition (OCR) and Set-of-Mark (SoM) prompting to enhance visual grounding capabilities. It is designed to be compatible with macOS, Windows, and Linux (with X server installed), and is released under the MIT license.
    Downloads: 12 This Week
    Last Update:
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  • 6
    ChemCrow

    ChemCrow

    Chemcrow

    ChemCrow is an AI-powered framework designed to assist in chemical research and discovery. It integrates AI models with chemical knowledge bases to provide intelligent recommendations for synthesis planning, reaction prediction, and material discovery. This tool helps automate and accelerate research in computational chemistry and drug development.
    Downloads: 11 This Week
    Last Update:
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  • 7
    Browser Use

    Browser Use

    Make websites accessible for AI agents

    Browser-Use is a framework that makes websites accessible for AI agents, enabling automated interactions and data extraction from web pages.
    Downloads: 10 This Week
    Last Update:
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  • 8
    OpenHands

    OpenHands

    Open-source autonomous AI software engineer

    Welcome to OpenHands (formerly OpenDevin), an open-source autonomous AI software engineer who is capable of executing complex engineering tasks and collaborating actively with users on software development projects. Use AI to tackle the toil in your backlog, so you can focus on what matters: hard problems, creative challenges, and over-engineering your dotfiles We believe agentic technology is too important to be controlled by a few corporations. So we're building all our agents in the open on GitHub, under the MIT license. Our agents can do anything a human developer can: they write code, run commands, and use the web. We're partnering with AI safety experts like Invariant Labs to balance innovation with security.
    Downloads: 9 This Week
    Last Update:
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  • 9
    smolagents

    smolagents

    Agents write python code to call tools and orchestrate other agents

    This library is the simplest framework out there to build powerful agents. We provide our definition in this page, where you’ll also find tips for when to use them or not (spoilers: you’ll often be better off without agents). smolagents is a lightweight framework for building AI agents using large language models (LLMs). It simplifies the development of AI-driven applications by providing tools to create, train, and deploy language model-based agents.
    Downloads: 8 This Week
    Last Update:
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  • 10
    AskUI Vision Agent

    AskUI Vision Agent

    Enable AI to control your desktop, mobile and HMI devices

    AskUI’s Vision Agent is an automation framework that allows you—and AI agents—to control real desktops, mobile devices, and HMI systems by perceiving the UI and performing actions like clicking, typing, scrolling, and drag-and-drop. It is designed for multi-platform compatibility and supports multiple AI models so you can tailor perception and decision-making to your workload. The repository presents a feature overview, sample media, and frequent release notes, which show ongoing improvements such as CORS checks and other operational tweaks. The broader AskUI documentation covers the Python Vision Agent along with suite services and inference APIs, indicating a productized ecosystem rather than a single library. Community-curated lists also recognize Vision Agent as part of the broader “GUI agents” landscape, placing it among other computer-use agents.
    Downloads: 7 This Week
    Last Update:
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  • 11
    CrewAI

    CrewAI

    Framework for orchestrating role-playing, autonomous AI agents

    Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks. The power of AI collaboration has too much to offer. CrewAI is designed to enable AI agents to assume roles, share goals, and operate in a cohesive unit - much like a well-oiled crew. Whether you're building a smart assistant platform, an automated customer service ensemble, or a multi-agent research team, CrewAI provides the backbone for sophisticated multi-agent interactions.
    Downloads: 7 This Week
    Last Update:
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  • 12
    LLMStack

    LLMStack

    No-code multi-agent framework to build LLM Agents, workflows

    LLMStack is a no-code platform for building generative AI agents, workflows and chatbots, connecting them to your data and business processes. Build tailor-made generative AI agents, applications and chatbots that cater to your unique needs by chaining multiple LLMs. Seamlessly integrate your own data, internal tools and GPT-powered models without any coding experience using LLMStack's no-code builder. Trigger your AI chains from Slack or Discord. Deploy to the cloud or on-premise.
    Downloads: 7 This Week
    Last Update:
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  • 13
    MindsDB

    MindsDB

    Making Enterprise Data Intelligent and Responsive for AI

    MindsDB is an AI data solution that enables humans, AI, agents, and applications to query data in natural language and SQL, and get highly accurate answers across disparate data sources and types. MindsDB connects to diverse data sources and applications, and unifies petabyte-scale structured and unstructured data. Powered by an industry-first cognitive engine that can operate anywhere (on-prem, VPC, serverless), it empowers both humans and AI with highly informed decision-making capabilities. A federated query engine that tidies up your data-sprawl chaos while meticulously answering every single question you throw at it. MindsDB has an MCP server built in that enables your MCP applications to connect, unify and respond to questions over large-scale federated data—spanning databases, data warehouses, and SaaS applications.
    Downloads: 7 This Week
    Last Update:
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  • 14
    Open AEA Framework

    Open AEA Framework

    A framework for open autonomous economic agent (AEA) development

    open-aea is an open-source framework for building autonomous software agents that can operate and interact independently on decentralized networks. Developed by Valory, it facilitates creating agents capable of economic transactions, communication, and smart contract interactions in Web3 ecosystems.
    Downloads: 7 This Week
    Last Update:
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  • 15
    Open Autonomy

    Open Autonomy

    A framework for the creation of autonomous agent services

    Open Autonomy is a framework that enables the development of autonomous economic agents (AEAs) capable of operating independently in various economic contexts.
    Downloads: 7 This Week
    Last Update:
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  • 16
    gpt-engineer

    gpt-engineer

    Full stack AI software engineer

    gpt-engineer is an open-source platform designed to help developers automate the software development process using natural language. The platform allows users to specify software requirements in plain language, and the AI generates and executes the corresponding code. It can also handle improvements and iterative development, giving users more control over the software they’re building. Built with a terminal-based interface, gpt-engineer is customizable, enabling developers to experiment with AI-assisted programming and refine their development process. It is especially useful for automating the coding and iterative feedback loop in software development.
    Downloads: 7 This Week
    Last Update:
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  • 17
    npcpy

    npcpy

    The AI toolkit for the AI developer

    npcpy is a Python-based agent framework and command-line toolkit (the NPC Shell) for developers to build, test, and integrate AI agents into their workflows, including both command-line and GUI interfaces via NPC Studio. Welcome to npcpy, the core library of the NPC Toolkit that supercharges natural language processing pipelines and agent tooling. npcpy is a flexible framework for building state-of-the-art applications and conducting novel research with LLMs. The structure of npcpy also allows one to pass an npc to get_llm_response in addition to using the NPC's wrapped method, allowing you to be flexible in your implementation and testing.
    Downloads: 7 This Week
    Last Update:
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  • 18
    Atomic Agents

    Atomic Agents

    Building AI agents, atomically

    The Atomic Agents framework is designed around the concept of atomicity to be an extremely lightweight and modular framework for building Agentic AI pipelines and applications without sacrificing developer experience and maintainability. The framework provides a set of tools and agents that can be combined to create powerful applications. It is built on top of Instructor and leverages the power of Pydantic for data and schema validation and serialization. All logic and control flows are written in Python, enabling developers to apply familiar best practices and workflows from traditional software development without compromising flexibility or clarity.
    Downloads: 6 This Week
    Last Update:
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  • 19
    Gemini Fullstack LangGraph Quickstart

    Gemini Fullstack LangGraph Quickstart

    Get started w/ building Fullstack Agents using Gemini 2.5 & LangGraph

    gemini-fullstack-langgraph-quickstart is a fullstack reference application from Google DeepMind’s Gemini team that demonstrates how to build a research-augmented conversational AI system using LangGraph and Google Gemini models. The project features a React (Vite) frontend and a LangGraph/FastAPI backend designed to work together seamlessly for real-time research and reasoning tasks. The backend agent dynamically generates search queries based on user input, retrieves information via the Google Search API, and performs reflective reasoning to identify knowledge gaps. It then iteratively refines its search until it produces a comprehensive, well-cited answer synthesized by the Gemini model. The repository provides both a browser-based chat interface and a command-line script (cli_research.py) for executing research queries directly. For production deployment, the backend integrates with Redis and PostgreSQL to manage persistent memory, streaming outputs, & background task coordination.
    Downloads: 6 This Week
    Last Update:
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  • 20
    OpenAI Agents SDK

    OpenAI Agents SDK

    A lightweight, powerful framework for multi-agent workflows

    The OpenAI Agents Python SDK is a powerful yet lightweight framework for developing multi-agent workflows. This framework enables developers to create and manage agents that can coordinate tasks autonomously, using a set of instructions, tools, guardrails, and handoffs. The SDK allows users to configure workflows in which agents can pass control to other agents as necessary, ensuring dynamic task management. It also includes a built-in tracing system for tracking, debugging, and optimizing agent activities.
    Downloads: 6 This Week
    Last Update:
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  • 21
    VectorizedMultiAgentSimulator (VMAS)

    VectorizedMultiAgentSimulator (VMAS)

    VMAS is a vectorized differentiable simulator

    VectorizedMultiAgentSimulator is a high-performance, vectorized simulator for multi-agent systems, focusing on large-scale agent interactions in shared environments. It is designed for research in multi-agent reinforcement learning, robotics, and autonomous systems where thousands of agents need to be simulated efficiently.
    Downloads: 6 This Week
    Last Update:
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  • 22
    Agent S2

    Agent S2

    Agent S: an open agentic framework that uses computers like a human

    Simular's Agent S2 represents a leap forward in the development of computer-use agents, capable of autonomously interacting with a range of devices and interfaces. By integrating specialized AI models, Agent S2 delivers state-of-the-art performance, whether on desktop systems or smartphones. Through modular architecture, it efficiently handles complex tasks, such as navigating UIs, performing low-level actions like text selection, and executing high-level strategies like planning. Additionally, the system's proactive hierarchical planning allows for real-time adaptation, making it an ideal solution for businesses seeking to streamline operations and automate digital workflows. Agent S2 is designed with flexibility, enabling seamless scaling for future applications and tasks.
    Downloads: 5 This Week
    Last Update:
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  • 23
    Agentic Security

    Agentic Security

    Agentic LLM Vulnerability Scanner / AI red teaming kit

    The open-source Agentic LLM Vulnerability Scanner.
    Downloads: 5 This Week
    Last Update:
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  • 24
    Composio

    Composio

    Composio equip's your AI agents & LLMs

    Empower your AI agents with Composio - a platform for managing and integrating tools with LLMs & AI agents using Function Calling. Equip your agent with high-quality tools & integrations without worrying about authentication, accuracy, and reliability in a single line of code.
    Downloads: 5 This Week
    Last Update:
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  • 25
    Dendrite

    Dendrite

    Tools to build web AI agents that can authenticate

    Dendrite Python SDK is a toolkit for building web AI agents that can authenticate, interact with, and extract data from any website, facilitating web automation tasks.
    Downloads: 5 This Week
    Last Update:
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