Best Digital Signature Software

Compare the Top Digital Signature Software as of November 2025

What is Digital Signature Software?

Digital signature software, also known as electronic signature or e-signature software. enables individuals and organizations to securely sign electronic documents using cryptographic technology that verifies authenticity, integrity, and signer identity. It replaces traditional handwritten signatures with legally recognized digital equivalents that comply with standards such as eIDAS, ESIGN, and UETA. These platforms use public key infrastructure (PKI) to encrypt and validate signatures, ensuring that documents cannot be altered after signing. Many solutions integrate with workflows, email, and document management systems to streamline contract approvals and reduce paperwork. By providing security, efficiency, and legal compliance, digital signature software has become essential for modern business transactions across industries. Compare and read user reviews of the best Digital Signature software currently available using the table below. This list is updated regularly.

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    Compliance Builder
    Compliance Builder™ is a real-time monitoring solution designed to enable 21 CFR Part 11 compliance, providing data integrity across IT systems such as file systems, database systems, laboratory or manufacturing instruments. By generating an audit trail and enabling electronic signatures, Compliance Builder allows you to securely track changes across all IT subsystems including file systems, databases, laboratory or manufacturing process equipment. It can be configured to monitor any file-based system for changes, including additions, deletions, and file modifications.
    Starting Price: 25000.00
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