Best Digital Signature Software
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Compare the Top Digital Signature Software as of November 2025
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What is Digital Signature Software?
Digital signature software, also known as electronic signature or e-signature software. enables individuals and organizations to securely sign electronic documents using cryptographic technology that verifies authenticity, integrity, and signer identity. It replaces traditional handwritten signatures with legally recognized digital equivalents that comply with standards such as eIDAS, ESIGN, and UETA. These platforms use public key infrastructure (PKI) to encrypt and validate signatures, ensuring that documents cannot be altered after signing. Many solutions integrate with workflows, email, and document management systems to streamline contract approvals and reduce paperwork. By providing security, efficiency, and legal compliance, digital signature software has become essential for modern business transactions across industries. Compare and read user reviews of the best Digital Signature software currently available using the table below. This list is updated regularly.
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1
Interfacing Enterprise Process Center (EPC)
Interfacing Technologies Corporation
Interfacing’s Enterprise Process Center (EPC) is an AI-powered Integrated Management System that unifies BPM, QMS, Document Control, and GRC into one platform. Organizations use EPC to model and automate processes, control documents, manage risks, and maintain regulatory compliance with full traceability and audit readiness. Built for highly regulated sectors such as aerospace, life sciences, finance, and government, EPC provides real-time visibility, automated workflows, and AI-driven insights that improve quality and reduce operational risk. The platform is ISO 27001 certified and fully validated for 21 CFR Part 11, making it suitable for mission-critical environments requiring strong governance, security, and control. EPC also includes low-code automation, process mining, audit management, training tracking, CAPA workflows, and dashboards to help teams streamline operations and continuously improve. AI strengthens governance, improves accuracy, and reinforces regulatory control.Starting Price: $10/month/user -
2
Odoo
Odoo
Odoo is a fully integrated, customizable, open-source software packed with hundreds of expertly designed business applications. Odoo’s intuitive database is able to meet a majority of business needs, such as: CRM, Sales, Project, Manufacturing, Inventory, and Accounting, just to name a few. Odoo is an all-in-one software solution designed to meet the needs of companies, regardless of their size (or budget). The unbeatable, seamless nature of Odoo helps businesses become more efficient by reducing redundant manual processes, which helps companies save countless hours of labor. Every module is interconnected to provide a fully-integrated experience from app to app, and users can automate many processes that would’ve otherwise required manual inputs into multiple applications. Odoo keeps all business functions in one place, allowing teams to collaborate with other departments from one unified platform in the most efficient way possible.Starting Price: $25.00/month/user -
3
SAP Business ByDesign
Navigator Business Solutions
The right ERP system for Life Sciences, Consumer Products & Distribution companies that are focused on growth and their systems are holding them back. Built for early-stage to mid-market companies that plan to grow. SAP Business ByDesign is a complete, cloud-based ERP solution for fast-growing, start-up to mid-market businesses and subsidiaries that want to scale without the complexity and unnecessary cost. With SAP Business ByDesign, you get an affordable way to manage your entire business as an integrated whole, from accounting and financials, purchasing, inventory, sales, and customer support, all the way to operations, logistics, project management, and human resources. 36 End-to-End Process Scenarios built-in Operational Performance Sourcing & Procurement Project Management Reporting & Analytics Accounting & Finance CRM, Sales, & Marketing Service Support Human resources (Suite-in-a-Box)Starting Price: $22 per/user/month -
4
Apptivo
Apptivo
Discover how Apptivo CRM Software can help attract, engage, retain and delight more customers. No more juggling between various apps. Increase your productivity and boost your client relationship by managing your Customers, Finances, and Support right from your pocket. Get all the following apps in one CRM, Invoices, Projects, Work Orders, Timesheets, Orders, Estimates, Help Desk, Expenses Reports. A simple online CRM system to store contacts, reminders, files, and communication history. If your business grows and you need more apps, feel free to add them from the App Store at anytime. Manage your sales pipeline, stay on top of employee activities, and close more deals. Track your sales and easily convert them into invoices to get paid quickly! Our mission is to reserve no effort to help our clients and their businesses to thrive and be successful. Everything you need in one cloud solution: CRM, Project Management, Invoicing & more.Starting Price: $10.00 per user per month -
5
Ultradox
floreysoft
With Ultradox you can automate tedious tasks and create your own business applications without hiring a team of developers. The unique combination of workflow and template engine allows you to combine, send and print documents, generate websites or send response emails as part of your process. In addition to automations that run in the background, like creating and sending weekly reports, you can also create interactive apps that engage multiple users, like approval flows. Share your app with your users or colleagues directly from Google Drive. Published apps follow material design guidelines and play well on both desktop and mobile devices. Ultradox has been created to allow people with or without coding skills to create applications. It's amazing to see what users with no coding experience have created.Starting Price: $29 per user per month -
6
GetBusy
GetBusy
Task Management Software. Organize your team with unmissable tasks. Focus your team with small, clear tasks that always get done. Packed with powerful features like online signatures. Trusted By Over 8,000 Teams. Small, clear tasks that always get done. These days critical tasks come from all directions, on different platforms, from different people. They often need the input of others to complete them. GetBusy’s task management software gets your work under control, making it unmissable, ordered and prioritized. Task Management. Imagine if your team always knew the who, what and when of every message. Client Requests. GetBusy isn't limited to your own team. Send tasks to anyone, anywhere – just like an email. Signatures. Exchange and sign legally binding documents at a fraction of the price of dedicated signature tools. File Requests. Chasing a file? Request confidential files as clear tasks. And much more secure than email.Starting Price: £30 per user per month -
7
Nucleus One
Ademero
Nucleus One is an all-in-one collaboration platform for modern businesses. Combining project management, document management, digital signatures, forms automation, public portals, an advanced workflow engine, and an AI assistant, it streamlines productivity and enhances team efficiency. Manage tasks seamlessly, store and access files easily, expedite approvals, create a professional online presence, and automate routine tasks with no-code setup. The AI assistant provides support, insights, and suggestions to help you make informed decisions. Experience unparalleled productivity and collaboration with Nucleus One.Starting Price: $10/month/user -
8
Sesame HR
Sesame HR
Sesame HR is a cloud-based human resources management platform designed to streamline and automate HR processes for businesses. It offers features like employee time tracking, absence management, payroll integration, and document management. The platform is user-friendly and helps companies simplify tasks such as managing employee records, monitoring performance, and ensuring compliance with labor regulations. Sesame HR also includes tools for employee self-service, allowing staff to request leave, track hours, and access documents, improving overall efficiency in HR operations.Starting Price: $4.25/user/month -
9
Moxo
Moxo
Moxo’s service orchestration platform transforms complex B2B relationships into seamless experiences. Business processes often fragment across departments, clients, vendors, and partners, creating inefficiency and risks. Our platform streamlines these workflows—turning disjointed experiences into smooth, efficient operations that reduce costs and enhance client satisfaction. Moxo accelerates critical processes including client onboarding, document collection, and exception handling. The results: faster completion times, reduced compliance risks, and superior client experiences. Leading institutions across financial services, consulting, legal, healthcare, and real estate—including Citibank and BNP Paribas —trust Moxo to orchestrate their mission-critical business relationships. -
10
Profiler Cloud
Profiler Cloud
Profiler Cloud is a suite of applications for digitizing every process in your company. With Profiler Cloud you digitize every aspect of your company, personnel management is no longer a problem with Docker, track attendance, distribute payslips and manage your employees' holidays and leave. With Graphit, you implement a graph metric signature process in a simple way in your ERP, allowing you to sign your files even on the move. Docker digitizes and simplifies the relationships between human resources and workers. With Graphit you can easily implement the graphometric signature in your company. Designed for the basic user, complete for the advanced user. Each element in Profiler Cloud is designed to be easily understood and assimilated by any type of user on any type of device. Profiler Cloud speeds up your work by integrating with most management software, without developing expensive customizations. You will be completely independent of enterprise software.
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