Best Digital Signature Software

Compare the Top Digital Signature Software as of November 2025

What is Digital Signature Software?

Digital signature software, also known as electronic signature or e-signature software. enables individuals and organizations to securely sign electronic documents using cryptographic technology that verifies authenticity, integrity, and signer identity. It replaces traditional handwritten signatures with legally recognized digital equivalents that comply with standards such as eIDAS, ESIGN, and UETA. These platforms use public key infrastructure (PKI) to encrypt and validate signatures, ensuring that documents cannot be altered after signing. Many solutions integrate with workflows, email, and document management systems to streamline contract approvals and reduce paperwork. By providing security, efficiency, and legal compliance, digital signature software has become essential for modern business transactions across industries. Compare and read user reviews of the best Digital Signature software currently available using the table below. This list is updated regularly.

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    SignCenter

    SignCenter

    Medforce Technologies

    SignCenter, a HIPAA-compliant web-based electronic signature and data capture solution, is suitable for healthcare organizations. With SignCenter, users are able to sign and mark documents using touchscreen, mouse, or keyboard from any device with internet connection. SignCenter enables users to manage the entire signature lifecycle in one place. SignCenter also records the time, date and IP address of the signer's device.
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