Compare the Top Digital Signature Software for Mac as of November 2025

What is Digital Signature Software for Mac?

Digital signature software, also known as electronic signature or e-signature software. enables individuals and organizations to securely sign electronic documents using cryptographic technology that verifies authenticity, integrity, and signer identity. It replaces traditional handwritten signatures with legally recognized digital equivalents that comply with standards such as eIDAS, ESIGN, and UETA. These platforms use public key infrastructure (PKI) to encrypt and validate signatures, ensuring that documents cannot be altered after signing. Many solutions integrate with workflows, email, and document management systems to streamline contract approvals and reduce paperwork. By providing security, efficiency, and legal compliance, digital signature software has become essential for modern business transactions across industries. Compare and read user reviews of the best Digital Signature software for Mac currently available using the table below. This list is updated regularly.

  • 1
    AS2 Gateway

    AS2 Gateway

    Aayu Technologies LLC

    Assured Trading with AS2 to Digitalize your Business. AS2 Gateway provides a B2B trading platform for organizations trading over the AS2 protocol, with a simplified and intuitive interface concealing the underlying complexities from end users. AS2 Gateway is fully compliant with the AS2 specification published by Drummond and Morberg, while ensuring the security of exchanged data via encryption, digital signature validation and guaranteed integrity through MIC (Message Integrity Check) hashing. Data security is further enhanced by utilizing the latest SSL/TLS channelling technologies as a supplementary security standard.
    Starting Price: $59 per month
  • 2
    Moxo

    Moxo

    Moxo

    Moxo’s service orchestration platform transforms complex B2B relationships into seamless experiences. Business processes often fragment across departments, clients, vendors, and partners, creating inefficiency and risks. Our platform streamlines these workflows—turning disjointed experiences into smooth, efficient operations that reduce costs and enhance client satisfaction. Moxo accelerates critical processes including client onboarding, document collection, and exception handling. The results: faster completion times, reduced compliance risks, and superior client experiences. Leading institutions across financial services, consulting, legal, healthcare, and real estate—including Citibank and BNP Paribas —trust Moxo to orchestrate their mission-critical business relationships.
  • 3
    SwissSign

    SwissSign

    SwissSign

    SwissSign enables you to make your processes and business transactions even more efficient by allowing customers and employees to sign easily online. Signature service by SwissSign: The Swiss signature solution from SwissSign offers qualified electronic signatures (QES) which are ZertEs (Swiss Signature Act) and eIDAS compliant as well as advanced (AES) and simple electronic signatures (SES). The solution that suits your needs: Regardless of whether you are a private individual, SME or large company, SwissID Sign offers the right solution for you. SwissSign offers a Ready-to-Go solution (no integration necessary) and an integration solution (cloud) based on “SwissID Sign”. For companies that require a flexible and confidential solution SwissSign recommends its On-premise solution “Let’s Sign”.
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