Best Microsegmentation Software

Compare the Top Microsegmentation Software as of October 2025

What is Microsegmentation Software?

Microsegmentation software is a data security solution that can be used to protect applications and data in cloud environments. It provides visibility into the network traffic within an organization, allowing users to set and enforce segmentation policies as needed. By creating micro-segments within the larger network environment, it helps to ensure that potential breaches are contained with minimum disruption. The software uses both analytics and automation to enforce these policies, helping to reduce the burden of manual tasks for IT teams. Finally, advanced features such as encryption and IDS/IPS help further protect an organization from threats and malicious actors. Compare and read user reviews of the best Microsegmentation software currently available using the table below. This list is updated regularly.

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    Cloudflare

    Cloudflare

    Cloudflare

    Cloudflare is the foundation for your infrastructure, applications, and teams. Cloudflare secures and ensures the reliability of your external-facing resources such as websites, APIs, and applications. It protects your internal resources such as behind-the-firewall applications, teams, and devices. And it is your platform for developing globally scalable applications. Your website, APIs, and applications are your key channels for doing business with your customers and suppliers. As more and more shift online, ensuring these resources are secure, performant and reliable is a business imperative. Cloudflare for Infrastructure is a complete solution to enable this for anything connected to the Internet. Behind-the-firewall applications and devices are foundational to the work of your internal teams. The recent surge in remote work is testing the limits of many organizations’ VPN and other hardware solutions.
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    Starting Price: $20 per website
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    Zscaler

    Zscaler

    Zscaler

    Zscaler, creator of the Zero Trust Exchange platform, uses the largest security cloud on the planet to make doing business and navigating change a simpler, faster, and more productive experience. The Zscaler Zero Trust Exchange enables fast, secure connections and allows your employees to work from anywhere using the internet as the corporate network. Based on the zero trust principle of least-privileged access, it provides comprehensive security using context-based identity and policy enforcement. The Zero Trust Exchange operates across 150 data centers worldwide, ensuring that the service is close to your users, co-located with the cloud providers and applications they are accessing, such as Microsoft 365 and AWS. It guarantees the shortest path between your users and their destinations, providing comprehensive security and an amazing user experience. Use our free service, Internet Threat Exposure Analysis. It’s fast, safe, and confidential.
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    Prisma Cloud

    Prisma Cloud

    Palo Alto Networks

    Comprehensive cloud native security. Prisma™ Cloud delivers comprehensive security across the development lifecycle on any cloud, enabling you to develop cloud native applications with confidence. The move to the cloud has changed all aspects of the application development lifecycle – security being foremost among them. Security and DevOps teams face a growing number of entities to secure as the organization adopts cloud native approaches. Ever-changing environments challenge developers to build and deploy at a frantic pace, while security teams remain responsible for the protection and compliance of the entire lifecycle. Firsthand accounts of Prisma Cloud’s best-in-class cloud security capabilities from some of our satisfied customers.
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    Akamai Guardicore Segmentation
    Akamai Guardicore Segmentation simplifies segmentation, reduce your attack surface and prevent lateral movement with fast and simple segmentation that works everywhere. Granular visibility and segmentation controls for Data Center, Cloud and Hybrid Cloud Environments. The Akamai Guardicore Segmentation Platform is the simplest and most intuitive way to visualize activity in data center and cloud environments, implement precise segmentation policies, protect against external threats, and detect possible breaches quickly. Akamai Guardicore Segmentation collects detailed information about an organization’s IT infrastructure through a mix of agent-based sensors, network-based data collectors, and virtual private cloud (VPC) flow logs from cloud providers. Relevant context is added to this information through a flexible and highly automated labeling process that includes integration with existing data sources like orchestration systems and configuration management databases.
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    Tufin

    Tufin

    Tufin

    Tufin enables organizations to automate their security policy visibility, risk management, provisioning and compliance across their multi-vendor, hybrid environment. Customers gain visibility and control across their network, ensure continuous compliance with security standards and embed security enforcement into workflows and development pipelines. Eliminate the security bottleneck and increase the business agility of your organization. Existing manual approaches to managing network changes can take weeks and introduce errors resulting in potential security risks. Organizations across the world rely on Tufin’s policy-based automation to automate visibility and provisioning and maximize business agility and security. Maintaining and demonstrating compliance with industry regulations and internal policies is difficult within today’s complex and fragmented networks. Tufin enables enterprises to ensure continuous compliance and maintain audit readiness.
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    Cisco Secure Workload
    Achieve the security required for today's heterogeneous multicloud environment with Cisco Secure Workload (formerly Tetration). Protect workloads across any cloud, application, and workload--anywhere. Automate and implement a secure zero-trust model for micro-segmentation based on application behavior and telemetry. Proactively detect and remediate indicators of compromise to minimize the impact to your business. Automate micro-segmentation through customized recommendations based on your environment and applications. Granular visibility and control over application components with automatic detection and enforcement of compliance. Track the security posture of applications across your entire environment. Make informed decisions using automatic NIST vulnerabilities data feed.
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