Best Microsegmentation Software

Compare the Top Microsegmentation Software as of October 2025

What is Microsegmentation Software?

Microsegmentation software is a data security solution that can be used to protect applications and data in cloud environments. It provides visibility into the network traffic within an organization, allowing users to set and enforce segmentation policies as needed. By creating micro-segments within the larger network environment, it helps to ensure that potential breaches are contained with minimum disruption. The software uses both analytics and automation to enforce these policies, helping to reduce the burden of manual tasks for IT teams. Finally, advanced features such as encryption and IDS/IPS help further protect an organization from threats and malicious actors. Compare and read user reviews of the best Microsegmentation software currently available using the table below. This list is updated regularly.

  • 1
    Faddom

    Faddom

    Faddom

    Faddom offers real-time, agentless application dependency mapping to give IT teams instant, risk-free visibility into hybrid environments. No credentials, no software installs, and no firewall changes. Faddom maps servers, applications, cloud resources, and traffic flows within an hour of deployment. This always-live mapping supports security audits, change impact analysis, cloud migration, IT documentation, and incident response. Faddom provides continuous infrastructure clarity without disruption, enabling better planning, control, and compliance. Trusted by organizations across industries, Faddom is built for speed, security, and simplicity. Deploy fast. Discover more. Stay in control.
    Starting Price: $0
  • 2
    Zscaler

    Zscaler

    Zscaler

    Zscaler, creator of the Zero Trust Exchange platform, uses the largest security cloud on the planet to make doing business and navigating change a simpler, faster, and more productive experience. The Zscaler Zero Trust Exchange enables fast, secure connections and allows your employees to work from anywhere using the internet as the corporate network. Based on the zero trust principle of least-privileged access, it provides comprehensive security using context-based identity and policy enforcement. The Zero Trust Exchange operates across 150 data centers worldwide, ensuring that the service is close to your users, co-located with the cloud providers and applications they are accessing, such as Microsoft 365 and AWS. It guarantees the shortest path between your users and their destinations, providing comprehensive security and an amazing user experience. Use our free service, Internet Threat Exposure Analysis. It’s fast, safe, and confidential.
  • 3
    12Port Horizon
    Our agentless platform allows you to quickly segment network workloads and restrict unauthorized traffic to prevent lateral movement and stop breaches. Protecting IT assets across physical, virtual, and cloud environments is increasingly complex. Traditional security can't counter sophisticated threats. Microsegmentation isolates workloads, monitors east-west traffic, and prevents lateral movement, ensuring attackers can't spread to critical areas and enhancing overall network security. Build and enforce security policies based on asset classification using hierarchical taxonomies and tagging. Enforce strict access controls and routinely monitor service traffic, aligning with zero trust principles to provide a comprehensive and flexible security strategy. 12Port Horizon features an agentless architecture, simplifying deployment and maintenance across physical, virtual, and cloud environments without adding complexity.
    Starting Price: $15 per month
  • 4
    Prisma Cloud

    Prisma Cloud

    Palo Alto Networks

    Comprehensive cloud native security. Prisma™ Cloud delivers comprehensive security across the development lifecycle on any cloud, enabling you to develop cloud native applications with confidence. The move to the cloud has changed all aspects of the application development lifecycle – security being foremost among them. Security and DevOps teams face a growing number of entities to secure as the organization adopts cloud native approaches. Ever-changing environments challenge developers to build and deploy at a frantic pace, while security teams remain responsible for the protection and compliance of the entire lifecycle. Firsthand accounts of Prisma Cloud’s best-in-class cloud security capabilities from some of our satisfied customers.
  • 5
    vArmour

    vArmour

    vArmour

    Legacy perimeters are irrelevant in modern cloud-based, remotely accessed, 24/7 enterprises. Hybrid environments are complex. People work from anywhere, at any time. But you still don’t know where all your applications, infrastructure, people, and data are, or the millions of dynamic interconnections among them. vArmour lets you automate, analyze, and act. Now. Based on what is happening currently or what happened last week. With no new agents. No new infrastructure. You are up and running fast with full coverage across your enterprise. Complete visibility means you create business and security policies to secure your assets and your business, significantly decreasing risk, ensuring compliance and building resiliency. Enterprise-wide protection built for the world of today, not yesterday.
  • 6
    Akamai Guardicore Segmentation
    Akamai Guardicore Segmentation simplifies segmentation, reduce your attack surface and prevent lateral movement with fast and simple segmentation that works everywhere. Granular visibility and segmentation controls for Data Center, Cloud and Hybrid Cloud Environments. The Akamai Guardicore Segmentation Platform is the simplest and most intuitive way to visualize activity in data center and cloud environments, implement precise segmentation policies, protect against external threats, and detect possible breaches quickly. Akamai Guardicore Segmentation collects detailed information about an organization’s IT infrastructure through a mix of agent-based sensors, network-based data collectors, and virtual private cloud (VPC) flow logs from cloud providers. Relevant context is added to this information through a flexible and highly automated labeling process that includes integration with existing data sources like orchestration systems and configuration management databases.
  • 7
    Tufin

    Tufin

    Tufin

    Tufin enables organizations to automate their security policy visibility, risk management, provisioning and compliance across their multi-vendor, hybrid environment. Customers gain visibility and control across their network, ensure continuous compliance with security standards and embed security enforcement into workflows and development pipelines. Eliminate the security bottleneck and increase the business agility of your organization. Existing manual approaches to managing network changes can take weeks and introduce errors resulting in potential security risks. Organizations across the world rely on Tufin’s policy-based automation to automate visibility and provisioning and maximize business agility and security. Maintaining and demonstrating compliance with industry regulations and internal policies is difficult within today’s complex and fragmented networks. Tufin enables enterprises to ensure continuous compliance and maintain audit readiness.
  • 8
    VMware Cloud Foundation
    Our new multi-cloud offering includes VMware Cloud Foundation-Subscription (includes Tanzu Standard), which adds a flexible term-based licensing option for on-premises deployments. VMware Cloud Foundation supports both traditional enterprise and modern apps and provides a complete set of highly secure software-defined services for compute, storage, network, security, Kubernetes and cloud management Increase enterprise agility and flexibility with consistent infrastructure and operations across private and public clouds. Achieve reduced CapEx and OpEx and lower TCO with consistent operations and the broadest range of deployment options. Run workloads at scale without compromise with consistent infrastructure for both existing enterprises applications and modern containerized applications. Provision agile infrastructure from a pool of virtualized resources on premises, at the edge, or in the cloud.
  • 9
    CloudGuard Network Security

    CloudGuard Network Security

    Check Point Software

    CloudGuard protects public, private and hybrid-cloud deployments from advanced threats with the highest catch rate of malware and other attacks. With CloudGuard Network Security, customers are ensured the easiest, quickest, and most secure cloud migration. Integrates with leading IaC tools for rapid deployment, agility, and automation of CI/CD workflows. Cutting-edge threat prevention with industry-leading catch rate of malware, ransomware and other types of attacks. Organizations with on-premises environments and in the process of migrating to the cloud are ensured unified and consistent security management of all their on-prem and cloud environments – experiencing the easiest, quickest and most secure cloud migration with lowest total cost of ownership and lowest organizational risk.
  • 10
    Opinnate

    Opinnate

    Opinnate

    As opposed to incumbent technologies, the intelligent and lightweight Opinnate platform makes automated network security policy management attainable for enterprises of all sizes. We offer numerous benefits that can help organizations improve their security posture, streamline operations, and comply with regulatory requirements. Every enterprise must keep its firewalls compliant with best practices and standards. Eliminate boundaries in network security policy management. Analyze, optimize, automate & audit your security policies easily. Rule optimization stands as a vital aspect in the maintenance and management of firewalls. Policy change automation becomes necessary when multiple firewalls, each from different vendors, are in place and there is a high volume of policy change requests. In multi-vendor topologies, the firewall policies may not be centrally managed since each vendor has its own management system.
  • 11
    ColorTokens Xtended ZeroTrust Platform
    The cloud-delivered ColorTokens Xtended ZeroTrust Platform protects from the inside out with unified visibility, micro-segmentation, zero-trust network access, cloud workload and endpoint protection. Visibility across on-premise & multiclouds. Micro-segment for cloud workload protection. Stop ransomware from owning your endpoints. See all communication between processes, files, users, applications, and workloads. Identify security gaps with built-in threat and vulnerability assessment. Simple and faster time-to-compliance (for HIPAA, PCI, GDPR). Easily create ZeroTrust Zones™ and drastically reduce the attack surface. Dynamic policies that protect workloads migrating to the cloud. Block lateral threats without cumbersome VLANs/ACLs or firewall rules. Lockdown any endpoint by automatically allowing only whitelisted processes. Block zero day or fileless exploits, and stop communication to C&C servers.
  • 12
    Cisco Secure Workload
    Achieve the security required for today's heterogeneous multicloud environment with Cisco Secure Workload (formerly Tetration). Protect workloads across any cloud, application, and workload--anywhere. Automate and implement a secure zero-trust model for micro-segmentation based on application behavior and telemetry. Proactively detect and remediate indicators of compromise to minimize the impact to your business. Automate micro-segmentation through customized recommendations based on your environment and applications. Granular visibility and control over application components with automatic detection and enforcement of compliance. Track the security posture of applications across your entire environment. Make informed decisions using automatic NIST vulnerabilities data feed.
  • 13
    Cisco Identity Services Engine (ISE)
    A critical component of any zero-trust strategy is securing the workplace that everyone and everything connects to. Cisco Identity Services Engine (ISE) enables a dynamic and automated approach to policy enforcement that simplifies the delivery of highly secure network access control. ISE empowers software-defined access and automates network segmentation within IT and OT environments.
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