Best Secure Email Gateway Software

Compare the Top Secure Email Gateway Software as of November 2025

What is Secure Email Gateway Software?

Secure email gateways protect organizations from email-based threats such as phishing, malware, spam, and data breaches. They analyze incoming and outgoing messages to detect suspicious content, malicious attachments, and unauthorized data sharing. These gateways enforce email security policies, filter harmful traffic, and provide encryption to safeguard sensitive communications. Many platforms also integrate with cloud email services like Microsoft 365 and Google Workspace to extend protection across hybrid environments. Ultimately, secure email gateways help maintain compliance, protect confidential information, and ensure safe, reliable business communication. Compare and read user reviews of the best Secure Email Gateway software currently available using the table below. This list is updated regularly.

  • 1
    N-able Mail Assure
    N-able Mail Assure cloud-based email security solution provides advanced threat protection for inbound and outbound email using collective threat intelligence, 24/7 email continuity, and long-term email archiving. The service includes a multitenant web-interface with predefined settings, reporting, and views designed to ensure control and visibility over email flows. N-able Mail Assure’s proprietary technology incorporates input from processing large volumes of email data that feeds the Intelligent Protection and Filtering Engine. This combined with real-time pattern threat recognition leveraging a variety of filtering technologies help protect against spam, viruses, phishing attacks, impersonation, spoofing, malware, and other email-borne threats.
  • 2
    SecurityGateway™ for Email Servers
    Developed by MDaemon Technologies, an email industry pioneer, Security Gateway's email threat detection technology has been protecting email servers from viruses, spam, phishing, data loss and other threats for over 20 years. Simply put, companies trust our expertise to help keep email communications safe. We protect all email platforms including Microsoft Exchange, Office 365 and others. Let our team of email security experts take the headache out of managing your company's email security needs. Security Gateway uses the latest email threat detection technology and policy enforcement tools to keep good emails flowing to and from your users. The Security Gateway cloud service can be deployed quickly and easily, allowing you to focus on other important tasks. Watch a short video to learn about some of the Security Gateway features.
    Starting Price: $1 per user per month
  • 3
    Symantec Email Security.cloud
    Safeguard Microsoft Office 365, Google G Suite, and on-premises email with the industry’s most complete email security solution. Insulate users from spear phishing, credential theft and ransomware attacks by using Email Threat Isolation. Prevent insidious email threats such as spear phishing, ransomware, business email compromise and email spam. Stop spear phishing emails with multiple layers of protection, threat isolation, spam filtering, advanced security email analytics, built-in user awareness, education tools, and more. Block the latest ransomware with content defense, sandboxing, and link protection technologies that detect emerging, stealthy, and zero-day attacks. Defeat business email compromise with impersonation protection, sender authentication enforcement and brand protection controls. Protect your brand reputation by using automation to solve the practical issues of enforcing sender authentication (DMARC, DKIM and SPF) with Symantec Email Fraud Protection.
  • 4
    Spambrella

    Spambrella

    Spambrella

    Dynamically classify imposter email. Preemptively identify and sandbox suspicious URLs. Leverage big-data analysis to accurately classify bulk mail. All within a single service that connects with Microsoft 365 and Google Workspace. Spambrella’s Email Security and User Awareness Training technology is used by some of the World’s largest and most successful security-conscious companies in a multitude of continents and environments. Delivered on a global scale, Spambrella is ready to unify your email security and user awareness training requirements. Think of us as your outsourced email security team! We have deep technical expertise of all other service providers such as MxLogic, Mimecast, Symantec.cloud and know how to migrate you effortlessly. Schedule a demo today with our cybersecurity experts to uncover email threats targeting your email users.
    Starting Price: $1.00
  • 5
    PhishProtection
    Make your smartest investment to reduce email security threats today, and get a comprehensive email security protection solution with small business pricing. Cybercriminals are targeting CEOs, CFOs, HR, Accounting Departments and regular employees across every industry. As you know Office 365 is extremely limited in the protection that you can configure to stop impersonations, email fraud and phishing. There are only so many custom transport rules you can build to constantly block domains or protect against employee impersonations. PhishProtection works on every email server, device or smtp service. No matter if you are on your phone, or outlook or any email client anywhere, we can protect you. It offers best-in-class security to iOS and Android devices alike.
    Starting Price: $100/month/user
  • 6
    Comodo Dome Antispam
    Secure Email Gateway is an enterprise anti-spam and threat prevention system that uses a sophisticated array of spam filters, anti-virus scanners and content analysis engines to prevent unsolicited mail from ever entering your network. Security needs differ from employee to employee. You may want to apply different security levels to different employees such as from finance or sales departments. Dome Anti-spam gives you the freedom to define different types of profiles with different security features and restrictions. Containment protects from the newest forms of ransomware, zero-malware, and other advanced threats. The Valkyrie file verdict system analyzes unknown files. Users are free to open, execute and use the attachments with ZERO risk of infection. Comodo's unique containment technology ensures that risks are fully contained before reaching the end point, so there is no risk of infection, even from the newest malware.
    Starting Price: $4.00/one-time/user
  • 7
    AppRiver

    AppRiver

    OpenText

    Unleash your teams to become more productive, secure, and compliant in a complex, digital world. Enhance your productivity, increase your security, and strengthen your compliance with the power of Secure Cloud. Reduce risks caused by human error and security-related obstacles to productivity. Threat detection and risk mitigation are constant, automated, and dynamic. Best-in-class email encryption, secure file sharing, and business communications archiving (email, social media, instant messaging). All services backed by 24/7/365 dedicated support from our phenomenal care team to better manage people, technology, and process. Automatic email encryption and data loss prevention offer unparalleled peace of mind for you, your employees and your executives. Prevent malware, ransomware and other advanced threats from compromising your email and your business.
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