Compare the Top USB Security Software for Windows as of November 2025

What is USB Security Software for Windows?

USB security software is a type of application designed to protect against malicious USB attacks. It can help keep your data safe by monitoring your USB ports for any unauthorized activity and preventing the transfer of any potentially dangerous files from unsecured flash drives. This software comes with various levels of protection, such as encryption, anti-malware scans, and real-time alerts. In addition, it can also provide you with an audit trail that tracks all activities associated with your USB ports. Lastly, these applications are simple to install and use yet can be highly effective in keeping your data secure against malicious attacks. Compare and read user reviews of the best USB Security software for Windows currently available using the table below. This list is updated regularly.

  • 1
    ThreatLocker

    ThreatLocker

    ThreatLocker

    The ThreatLocker suite of security tools are powerful and designed so that everyone from businesses to government agencies to academic institutions can directly control exactly what applications run on their networks. We envision a future in which all organizations can chart their own course free from the influence of cybercriminals and the damage their incursions cause, and our team of veteran cybersecurity professionals created ThreatLocker to make this vision a reality. The team at ThreatLocker has been developing cybersecurity tools for decades, including programs to enhance email and content security, and this is our most innovative and ambitious cybersecurity solution yet. We developed this unique cybersecurity system because we believe that organizations should have complete control of their networks and should not have to live in fear of the next malware attack. To learn more, visit ThreatLocker.com.
    Leader badge
    Partner badge
    View Software
    Visit Website
  • 2
    Safetica

    Safetica

    Safetica

    Safetica’s Intelligent Data Security protects sensitive data where teams work, using powerful AI to deliver contextual awareness, reduce false positives, and stop real threats without disrupting productivity. With Safetica, security teams can maintain visibility and control over sensitive data, stay ahead of insider risks, maintain compliance, and secure sensitive cloud-based data. ✔️ Data Protection: Classify, monitor and control sensitive data across devices and clouds in real time. ✔️ Insider Risk and User Behavior: Spot risky behavior, detect intent, and stop insider threats to stay ahead of the careless handling of sensitive data, compromised user accounts and malicious user activity. ✔️ Compliance and Data Discovery: Prove compliance with audit-ready reporting for data in use, in motion, and at rest. ✔️ Cloud Security: Protect Microsoft 365, cloud, and file-sharing platforms to secure sensitive cloud-based data.
    Leader badge
    Partner badge
    View Software
    Visit Website
  • 3
    Bitdefender GravityZone
    Bitdefender GravityZone provides full visibility into organizations' overall security posture, global security threats, and control over its security services that protect virtual or physical desktops, servers and mobile devices. All Bitdefender's Enterprise Security solutions are managed within the GravityZone through a single console, Control Center, that provides control, reporting, and alerting services for various roles within the organization
  • 4
    USB-LOCK-RP

    USB-LOCK-RP

    Advanced Systems International

    USB Control & Lockdown Software to Block USB Devices Access and Lock USB Ports in Windows Systems. Centralized USB Device Management, Monitoring and Whitelisting to Protect Computers in a Network. USB Device Control is an important part of Endpoint Security Management and focuses in the protection of computer systems and data assets from threats posed by unauthorized USB device usage. Controlling USB devices access to endpoints is required to secure networks that control machinery or store sensitive information. - Centralized USB Device Management. - Secures Groups of Computer or Specific Computers. - Whitelists Specific Devices by Hardware ID and Blocks the rest. -Automatically apply Group 1 protection settings to unassigned clients. NEW! - Receives Alerts & Logs Device Connections in the Network Automatically. -Export Status and Alerts Reports to csv format (Comma-separated value)NEW! -Automatic Authorizations Mode, Whitelist USB devices across the network automatically. NEW
    Starting Price: $20 per client/one-time
  • 5
    Endpoint Protector
    Endpoint Protector is an advanced, all-in-one Data Loss Prevention solution for Windows, macOS and Linux, that puts an end to data leaks and data theft and offers seamless control of portable storage devices. Endpoint Protector’s filtering capabilities for data at rest and in motion range from file type to predefined content based on dictionaries, regular expressions or data protection regulations such as GDPR, PCI DSS, CCPA, HIPAA, etc. Endpoint Protector features several specialized modules that can be mixed and matched based on client needs. The modules comprise: Content Aware Protection, Device Control, Enforced Encryption, and eDiscovery . It makes work more convenient, secure and enjoyable, offering an excellent ROI.
  • 6
    AccessPatrol

    AccessPatrol

    CurrentWare Inc.

    AccessPatrol is a data loss prevention and USB device control software that provides a proactive solution for preventing data breaches caused by illicit data transfers. AccessPatrol controls a variety of peripherals, including… - Storage devices such as USB flash drives and external hard drives - Wireless Devices such as Bluetooth, Infrared, and WiFi - Communication Ports such as Serial and Parallel ports - Imaging Devices such as Scanners or Cameras, and… - Other Devices such as network share drives, printers, and mobile phones File operations alerts and permissions can be configured to alert IT administrators to suspicious file operations and proactively prevent data transfers to unauthorized users. The security policies are enforced by a software agent that is installed on your user’s computers. This keeps devices restricted and monitored even when the computers are taken off of the network.
    Starting Price: $6 PUPM
  • 7
    BUFFERZONE

    BUFFERZONE

    Bufferzone Security

    BUFFERZONE provides a patented containment and disarming solution that defends endpoints against advanced malware and zero-day attacks while maximizing user and IT productivity. By isolating potentially malicious content coming from browsers, email and removable media, BUFFERZONE defends individuals and organizations from advanced threats that evade detection. BUFFERZONE disarms content for securely transferring it from the container to the native endpoint and secure network zones, and provides critical intelligence for enterprise-wide security analytics. Easy to deploy and configure, BUFFERZONE is a lightweight solution that provides cost-effective containment for up to thousands of endpoints.
  • 8
    ManageEngine Device Control Plus
    Device Control Plus is an enterprise software, specially designed for complete device control and file access management. It is equipped with an intuitive interface using which the admin can efficiently classify USB and other peripheral devices as trusted, blocked or allowed temporary access. It is also equipped with numerous data security capabilities including assigning read-only file access, restricting file copying or blocking unauthorized file transfers. Additionally for extensive visibility over device actions and forensic analysis of policy efficacy and network performance, file tracing and file shadowing reports will be automatically generated. Know who is using what device on which endpoint with clear-cut audit data and reports, and receive instant alerts in case of unauthorized access.
    Starting Price: $5.95 per user per year
  • 9
    Acronis DeviceLock DLP
    Acronis DeviceLock DLP provides comprehensive endpoint DLP (endpoint data loss prevention) – discovering and protecting sensitive data while monitoring the operations involving that information. Prevent data leakage due to employee negligence or malicious insiders by blocking any unauthorized attempt to access or transfer data, discovering and protecting sensitive data-at-rest. Reduce the complexity of data protection and cut reporting times with a single DLP solution for thorough visibility over data flows and user behavior. Reduce information security risks and comply with IT security standards and regulations by enforcing data use and handling policies that users can’t avoid following. Save the time and hassle associated with managing a DLP solution. Acronis DeviceLock DLP is easily deployable through Active Directory (AD) and offers various central management consoles, based on your organization’s requirements.
    Starting Price: $615 one-time payment
  • Previous
  • You're on page 1
  • Next