Compare the Top Virtual Desktop (VDI) Software in the USA as of November 2025

What is Virtual Desktop (VDI) Software in the USA?

Virtual Desktop Infrastructure (VDI) software enables users to create and run virtual desktops and virtual desktop environments in order to execute and run multiple cloud desktops and operating systems on a single computer or in the cloud. Compare and read user reviews of the best Virtual Desktop (VDI) software in the USA currently available using the table below. This list is updated regularly.

  • 1
    V2 Cloud

    V2 Cloud

    V2 Cloud Solutions

    V2 Cloud offers powerful, secure, and fully managed virtual desktops accessible from anywhere. Our platform is purpose-built for Independent Software Vendors, Managed Service Providers, IT professionals, and business owners looking to streamline operations, improve security, and scale efficiently. With V2 Cloud, you can easily start your desktops and apps in the cloud, enabling secure remote work from anywhere. Plus, you can access fully managed IT services, proactive security, and responsive support to scale effortlessly. Get the business resiliency you need! Boost your performance with the GPU-enhanced virtual machine and start working with heavy applications without crashes. Enjoy fast and professional support with global multilingual support. Discover how simple and cost-effective desktop virtualization can be with V2 Cloud. Try it today!
    Starting Price: $40 per month
  • 2
    VirtualBox
    VirtualBox is a powerful x86 and AMD64/Intel64 virtualization product for enterprise as well as home use. Not only is VirtualBox an extremely feature rich, high performance product for enterprise customers, it is also the only professional solution that is freely available as Open Source Software under the terms of the GNU General Public License (GPL) version 2. See "About VirtualBox" for an introduction. Presently, VirtualBox runs on Windows, Linux, Macintosh, and Solaris hosts and supports a large number of guest operating systems including but not limited to Windows (NT 4.0, 2000, XP, Server 2003, Vista, Windows 7, Windows 8, Windows 10), DOS/Windows 3.x, Linux (2.4, 2.6, 3.x and 4.x), Solaris and OpenSolaris, OS/2, and OpenBSD. VirtualBox is being actively developed with frequent releases and has an ever growing list of features, supported guest operating systems and platforms it runs on. VirtualBox is a community effort backed by a dedicated company.
  • 3
    Nerdio
    Empowering Managed Service Providers & Enterprise IT Professionals to quickly and easily deploy Azure Virtual Desktop and Windows 365, manage all environments from one simple platform, and optimize costs by saving up to 75% on Azure compute and storage. Nerdio Manager for Enterprise extends the native Azure Virtual Desktop and Windows 365 admin capabilities with automatic and fast virtual desktop deployment, simple management in just a few clicks, and cost-optimization features for savings of up to 75% – paired with the unmatched security of Microsoft Azure and expert-level Nerdio support. Nerdio Manager for MSP is a multi-tenant Azure Virtual Desktop and Windows 365 deployment, management, and optimization platform for Managed Service Providers that allows for automatic provisioning in under an hour (or connect to an existing deployment in minutes), management of all customers in a simple admin portal, and cost-optimization with Nerdio’s Advanced Auto-scaling.
    Starting Price: $100 per month
  • 4
    Scale Computing Platform
    SC//Platform brings faster time to value in the data center, in the distributed enterprise, and at the edge. Scale Computing Platform brings simplicity, high availability and scalability together, replacing the existing infrastructure and providing high availability for running VMs in a single, easy-to-manage platform. Run your applications in a fully integrated platform. Regardless of your hardware requirements, the same innovative software and simple user interface give you the power to run infrastructure efficiently at the edge. Eliminate mundane management tasks and save the valuable time of IT administrators. The simplicity of SC//Platform directly impacts IT with higher productivity and lower costs. Plan the perfect future by not predicting it. Simply mix and match old and new hardware and applications on the same infrastructure for a future-proof environment that can scale up or down as needed.
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