diff --git a/modules/cmsis/CMakeLists.txt b/modules/cmsis/CMakeLists.txt
index 59a8307a8fb..d23bcaea979 100644
--- a/modules/cmsis/CMakeLists.txt
+++ b/modules/cmsis/CMakeLists.txt
@@ -3,6 +3,6 @@
 
 add_subdirectory(${ZEPHYR_CURRENT_MODULE_DIR} cmsis)
 
-if(CONFIG_CPU_CORTEX_M OR CONFIG_CPU_AARCH32_CORTEX_A OR CONFIG_CPU_AARCH32_CORTEX_R)
+if(CONFIG_CPU_AARCH32_CORTEX_A OR CONFIG_CPU_AARCH32_CORTEX_R)
   zephyr_include_directories(.)
 endif()
diff --git a/modules/cmsis/Kconfig b/modules/cmsis/Kconfig
index aba63d35e1a..9cc5ee79630 100644
--- a/modules/cmsis/Kconfig
+++ b/modules/cmsis/Kconfig
@@ -8,7 +8,6 @@ config HAS_CMSIS_CORE
 	bool
 	select HAS_CMSIS_CORE_A if CPU_AARCH32_CORTEX_A
 	select HAS_CMSIS_CORE_R if CPU_AARCH32_CORTEX_R
-	select HAS_CMSIS_CORE_M if CPU_CORTEX_M
 
 if HAS_CMSIS_CORE
 
@@ -18,19 +17,4 @@ config HAS_CMSIS_CORE_A
 config HAS_CMSIS_CORE_R
 	bool
 
-config HAS_CMSIS_CORE_M
-	bool
-
-config CMSIS_M_CHECK_DEVICE_DEFINES
-	bool "Check device defines"
-	default n
-	depends on HAS_CMSIS_CORE_M
-	help
-	  This options enables the validation of CMSIS configuration flags.
-
-config CMSIS_CORE_HAS_SYSTEM_CORE_CLOCK
-	bool
-	help
-	  Enable this option if CMSIS SystemCoreClock symbols is available.
-
 endif
diff --git a/modules/cmsis/cmsis_core.h b/modules/cmsis/cmsis_core.h
index 4f57c682138..b85533b56ae 100644
--- a/modules/cmsis/cmsis_core.h
+++ b/modules/cmsis/cmsis_core.h
@@ -6,9 +6,7 @@
 #ifndef ZEPHYR_MODULES_CMSIS_CMSIS_H_
 #define ZEPHYR_MODULES_CMSIS_CMSIS_H_
 
-#if defined(CONFIG_CPU_CORTEX_M)
-#include "cmsis_core_m.h"
-#elif defined(CONFIG_CPU_AARCH32_CORTEX_A) || defined(CONFIG_CPU_AARCH32_CORTEX_R)
+#if defined(CONFIG_CPU_AARCH32_CORTEX_A) || defined(CONFIG_CPU_AARCH32_CORTEX_R)
 #include "cmsis_core_a_r.h"
 #endif
 
diff --git a/modules/cmsis_6/CMakeLists.txt b/modules/cmsis_6/CMakeLists.txt
new file mode 100644
index 00000000000..1f501f45342
--- /dev/null
+++ b/modules/cmsis_6/CMakeLists.txt
@@ -0,0 +1,9 @@
+# Copyright (c) 2023 Nordic Semiconductor ASA
+# Copyright 2025 Arm Limited and/or its affiliates <open-source-office@arm.com>
+# SPDX-License-Identifier: Apache-2.0
+
+add_subdirectory(${ZEPHYR_CURRENT_MODULE_DIR} cmsis_6)
+
+if(CONFIG_CPU_CORTEX_M)
+  zephyr_include_directories(.)
+endif()
diff --git a/modules/cmsis_6/Kconfig b/modules/cmsis_6/Kconfig
new file mode 100644
index 00000000000..6da2792698e
--- /dev/null
+++ b/modules/cmsis_6/Kconfig
@@ -0,0 +1,28 @@
+# Copyright (c) 2016 Intel Corporation
+# Copyright 2025 Arm Limited and/or its affiliates <open-source-office@arm.com>
+# SPDX-License-Identifier: Apache-2.0
+
+config ZEPHYR_CMSIS_6_MODULE
+	bool
+
+config HAS_CMSIS_CORE
+	bool
+	select HAS_CMSIS_CORE_M if CPU_CORTEX_M
+
+if HAS_CMSIS_CORE
+
+config HAS_CMSIS_CORE_M
+	bool
+
+config CMSIS_M_CHECK_DEVICE_DEFINES
+	bool "Check device defines"
+	depends on HAS_CMSIS_CORE_M
+	help
+	  This options enables the validation of CMSIS configuration flags.
+
+config CMSIS_CORE_HAS_SYSTEM_CORE_CLOCK
+	bool
+	help
+	  Enable this option if CMSIS SystemCoreClock symbols is available.
+
+endif
diff --git a/modules/cmsis_6/cmsis_core.h b/modules/cmsis_6/cmsis_core.h
new file mode 100644
index 00000000000..3d85be7a396
--- /dev/null
+++ b/modules/cmsis_6/cmsis_core.h
@@ -0,0 +1,14 @@
+/*
+ * Copyright (c) 2023 Nordic Semiconductor ASA
+ * Copyright 2025 Arm Limited and/or its affiliates <open-source-office@arm.com>
+ * SPDX-License-Identifier: Apache-2.0
+ */
+
+#ifndef ZEPHYR_MODULES_CMSIS_6_CMSIS_CORE_H_
+#define ZEPHYR_MODULES_CMSIS_6_CMSIS_CORE_H_
+
+#if defined(CONFIG_CPU_CORTEX_M)
+#include "cmsis_core_m.h"
+#endif
+
+#endif /* ZEPHYR_MODULES_CMSIS_6_CMSIS_CORE_H_ */
diff --git a/modules/cmsis/cmsis_core_m.h b/modules/cmsis_6/cmsis_core_m.h
similarity index 90%
rename from modules/cmsis/cmsis_core_m.h
rename to modules/cmsis_6/cmsis_core_m.h
index c8552f0ee77..4137e853376 100644
--- a/modules/cmsis/cmsis_core_m.h
+++ b/modules/cmsis_6/cmsis_core_m.h
@@ -1,6 +1,6 @@
 /*
  * Copyright (c) 2017 Nordic Semiconductor ASA
- * Copyright (c) 2023 Arm Limited
+ * Copyright 2023,2025 Arm Limited and/or its affiliates <open-source-office@arm.com>
  *
  * SPDX-License-Identifier: Apache-2.0
  */
@@ -12,8 +12,8 @@
  * This header contains the interface to the ARM CMSIS Core headers.
  */
 
-#ifndef ZEPHYR_MODULES_CMSIS_CMSIS_M_H_
-#define ZEPHYR_MODULES_CMSIS_CMSIS_M_H_
+#ifndef ZEPHYR_MODULES_CMSIS_6_CMSIS_CORE_M_H_
+#define ZEPHYR_MODULES_CMSIS_6_CMSIS_CORE_M_H_
 
 #if defined(CONFIG_CMSIS_M_CHECK_DEVICE_DEFINES) && CONFIG_CMSIS_M_CHECK_DEVICE_DEFINES == 1U
 #define __CHECK_DEVICE_DEFINES 1U
@@ -68,4 +68,4 @@
 #error "__SAUREGION_PRESENT and CONFIG_CPU_HAS_ARM_SAU are not set to the same value"
 #endif
 
-#endif /* ZEPHYR_MODULES_CMSIS_CMSIS_M_H_ */
+#endif /* ZEPHYR_MODULES_CMSIS_6_CMSIS_CORE_M_H_ */
diff --git a/modules/cmsis/cmsis_core_m_defaults.h b/modules/cmsis_6/cmsis_core_m_defaults.h
similarity index 93%
rename from modules/cmsis/cmsis_core_m_defaults.h
rename to modules/cmsis_6/cmsis_core_m_defaults.h
index f2c0656d220..bb084440ef7 100644
--- a/modules/cmsis/cmsis_core_m_defaults.h
+++ b/modules/cmsis_6/cmsis_core_m_defaults.h
@@ -1,6 +1,6 @@
 /*
  * Copyright (c) 2017 Nordic Semiconductor ASA
- * Copyright (c) 2023 Arm Limited
+ * Copyright 2023,2025 Arm Limited and/or its affiliates <open-source-office@arm.com>
  *
  * SPDX-License-Identifier: Apache-2.0
  */
@@ -13,8 +13,8 @@
  * ARM CMSIS Core headers.
  */
 
-#ifndef ZEPHYR_MODULES_CMSIS_CMSIS_M_DEFAULTS_H_
-#define ZEPHYR_MODULES_CMSIS_CMSIS_M_DEFAULTS_H_
+#ifndef ZEPHYR_MODULES_CMSIS_6_CMSIS_CORE_M_DEFAULTS_H_
+#define ZEPHYR_MODULES_CMSIS_6_CMSIS_CORE_M_DEFAULTS_H_
 
 #include <zephyr/arch/arm/cortex_m/nvic.h>
 
@@ -143,4 +143,4 @@ typedef enum {
 #error "Unknown Cortex-M device"
 #endif
 
-#endif /* ZEPHYR_MODULES_CMSIS_CMSIS_M_DEFAULTS_H_ */
+#endif /* ZEPHYR_MODULES_CMSIS_6_CMSIS_CORE_M_DEFAULTS_H_ */
diff --git a/modules/trusted-firmware-m/CMakeLists.txt b/modules/trusted-firmware-m/CMakeLists.txt
index ff4a3093fdc..716c53ab2cf 100644
--- a/modules/trusted-firmware-m/CMakeLists.txt
+++ b/modules/trusted-firmware-m/CMakeLists.txt
@@ -289,7 +289,7 @@ if (CONFIG_BUILD_WITH_TFM)
       ${TFM_CMAKE_ARGS}
       $<GENEX_EVAL:$<TARGET_PROPERTY:zephyr_property_target,TFM_CMAKE_OPTIONS>>
       -DMBEDCRYPTO_PATH=$<IF:$<BOOL:$<TARGET_PROPERTY:zephyr_property_target,TFM_MBEDCRYPTO_PATH>>,$<TARGET_PROPERTY:zephyr_property_target,TFM_MBEDCRYPTO_PATH>,${ZEPHYR_MBEDTLS_MODULE_DIR}>
-      -DCMSIS_PATH=${ZEPHYR_TRUSTED_FIRMWARE_M_MODULE_DIR}/platform/ext/cmsis
+      -DCMSIS_PATH=${ZEPHYR_CMSIS_6_MODULE_DIR}
       ${ZEPHYR_TRUSTED_FIRMWARE_M_MODULE_DIR}
     WORKING_DIRECTORY ${TFM_BINARY_DIR}
     COMMAND_EXPAND_LISTS
diff --git a/west.yml b/west.yml
index 984bb9c21b2..53598678f06 100644
--- a/west.yml
+++ b/west.yml
@@ -129,8 +129,10 @@ manifest:
       path: modules/lib/cmsis-nn
     - name: cmsis_6
       repo-path: CMSIS_6
-      revision: 783317a3072554acbac86cca2ff24928cbf98d30
-      path: modules/lib/cmsis_6
+      revision: 6dd50439a9b83398ff2ae1376eef0a2a0b95913b
+      path: modules/hal/cmsis_6
+      groups:
+        - hal
     - name: edtt
       revision: b9ca3c7030518f07b7937dacf970d37a47865a76
       path: tools/edtt
@@ -358,7 +360,7 @@ manifest:
       groups:
         - tee
     - name: trusted-firmware-m
-      revision: e2288c13ee0abc16163186523897e7910b03dd31
+      revision: 64738996dca5f5e058e0a358b81033f4b792be27
       path: modules/tee/tf-m/trusted-firmware-m
       groups:
         - tee