The two most powerful words in the English language, owed entirely to the efficacy of vaccines, are thus;
For most of history, smallpox was (!!!) the scourge that haunted human civilisations. We have evidence of smallpox from mummies c. 1350BCE in Egypt. It’s speculated to be one of causative agents of the Plague of Athens c. 430BCE. There were outbreaks of smallpox in Angola in 1484, in South Africa in 1731 that wiped out entire clans of Khoisan people. There was at least one major smallpox epidemic almost every decade across Europe.
Smallpox was transmitted by droplet/aerosol infection; it tore through even the smallest population centres. Typical smallpox incurred a blistering fever, raised pustules, debilitating joint and back pain; if you lived — and that was a fat fucking if, as typical smallpox had a mortality rate of 30% — you’d have tell-tale pockmark scarring, and face stigma for the rest of your life. Some were left blinded.
The worst form of the disease was haemorrhagic smallpox; all the agony of typical smallpox, with the addition of skin haemorrhage and pinpoint haemorrhage in the spleen, liver, kidneys and gonads. Near-universally fatal, haemorrhagic smallpox made up 5-10% of all cases. Of this number, 72% were children.
The global smallpox vaccination campaigns of 1958 to 1977 were a monumental effort by the World Health Organization and its global associates, backed by incredibly diligent public health work and epidemiological monitoring.
Wherever there were outbreaks, there was herd immunisation. Health bodies campaigned tirelessly for the general population to be immunised. In the ‘70s, a concerted effort was made by the WHO to ensure vaccines were administered in the most remote and vulnerable communities in the Horn of Africa, South Asia and the Pacific.
In 1980, the world was officially, finally free of one of it’s oldest adversaries; universal vaccination had been achieved, and there was no population that could act as a reservoir for smallpox.
If mankind has only one great achievement, it’s the smallpox vaccine; to date, smallpox is the only human disease to be completely eradicated.
After over two millennia of suffering, mass disability and death, humanity finally had the means to give one of it’s biggest threats the biggest possible fuck you, and through scientific and public health collaboration, careful epidemiological monitoring and countless hours of on-the-ground vaccination efforts, managed to blot it from existence entirely.
Where there is vaccine coverage, childhood diseases with high morbidity and mortality rates like whooping cough, diphtheria, influenza B and have dropped.
We have vaccines for TB, another of our greatest and longest adversaries.
With enough effort to counter misinformation, more people fighting for vaccine equality, patent free medication for communicable disease, and universal vaccine coverage, and everyone making sure to keep up to date with their vaccinations, one day, we could be fortunate enough to be able to say;