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Biosafety and Biosecurity

This document summarizes key concepts regarding laboratory biosafety and biosecurity. It defines biosafety as practices that prevent accidental exposure to pathogens or their release, protecting people from germs. Biosecurity refers to protecting valuable biological materials from unauthorized access or intentional release, protecting germs from people. It also outlines different risk groups for classifying microorganisms based on their danger, as well as biosafety levels 1 through 4 which require increasing containment practices based on the risk group of the microorganisms being handled. Finally, it lists some organizations involved in promoting biosafety.

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Micah Leila
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59 views

Biosafety and Biosecurity

This document summarizes key concepts regarding laboratory biosafety and biosecurity. It defines biosafety as practices that prevent accidental exposure to pathogens or their release, protecting people from germs. Biosecurity refers to protecting valuable biological materials from unauthorized access or intentional release, protecting germs from people. It also outlines different risk groups for classifying microorganisms based on their danger, as well as biosafety levels 1 through 4 which require increasing containment practices based on the risk group of the microorganisms being handled. Finally, it lists some organizations involved in promoting biosafety.

Uploaded by

Micah Leila
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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basic concepts on

LABORATORY
BIOSAFETY
AND
BIOSECURITY
Gabriel Vincent M. Grecia, RMT
BIOSAFETY
“The containment principles, technologies, and
practices that are implemented to prevent
unintentional exposure to pathogens and
toxins or their accidental release”
“Biosafety protects
PEOPLE from GERMS”
BIOSECURITY
“The protection, control, and
accountability for valuable biological
materials within laboratories in order to
prevent their unauthorized access, lost,
theft, misuse, diversion or intentional
release”
“Biosecurity protects
GERMS from PEOPLE”
ORGANIZATIONS IN THE FIELD OF
BIOSAFETY
1. American Biological Safety
Accreditation (ABSA)
2. Asia- Pacific Biosafety Association
(APBA)
3. European Biological Safety
Association (EBSA)
ORGANIZATIONS IN THE FIELD OF
BIOSAFETY

4. Philippine Biosafety and Biosecurity


Association (PhBBA)
5. Biological Risk Association
Philippines (BRAP)
Classification Of
Microorganisms
According To
Risk Groups
RISK GROUP 1
 Non Pathogenic
 LOW individual and community risk
RISK GROUP 2
 May cause infection but effective treatment
and preventative measures are available
 risk of spread is limited
 MODERATE individual and community risk
RISK GROUP 3
 Microorganism cause
serious diseases
 Effective treatment and
preventive measures are
present
 moderate risk of
transmission
 HIGH individual risk and
LIMITED TO MODERATE
community risk
RISK GROUP 4
 Microorganisms cause life threatening diseases
 Treatment and preventive measures are not
available
 Readily transmissible
 HIGH individual and community risk
BSL 4

BSL 3 BIOSAFETY
LEVELS
BSL 2

BSL 1
“All laboratory regardless of
their biosafety level must
follow
BASIC GOOD LABORATORY
PRACTICES”
BIOSAFETY LEVEL 1

 Non pathogenic microorganisms


 Standard Practices
 PPE
 Lab Bench and sink required
BIOSAFETY LEVEL 2
Agents causes diseases in humans
 BSL 1 Practices plus:
 Limited access
 Warning signs
 Sharps precaution
 Biosafety manual
BIOSAFETY LEVEL 2
Biosafety Cabinets
 for manipulation of agents
that cause splashes or aerosols
of infectious material
PPE
 BSL 1 facilities plus:
 AUTOCLAVE
BIOSAFETY LEVEL 3
Agents cause serious disease
through inhalation
BSL 2 practices plus
 Controlled access
 Decontamination of all waste
 Decontamination of lab
clothing
BIOSAFETY LEVEL 3
 Biosafety Cabinet
 use for all open manipulation
of agents
 PPE
BIOSAFETY LEVEL 3
 BSL 2 facilities plus:
 Self closing, double door
 Exhausted air not recirculated
 Negative airflow
 Entry through airlock or
anteroom
 Handwashing sink near exit
BIOSAFETY LEVEL 4
 Agents cause fatal diseases for which
there are no vaccines or treatment.
 BSL 3 practices plus:
 Clothing change before entering
 Shower on exit
 All material decontaminated on exit
from facility
BIOSAFETY LEVEL 4
 Class III Biosafety cabinet
OR
 Class I or II Biosafety cabinet plus
 Full body, air-supplied, positive
pressure suit
END OF
PRESENTATION

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