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life science term 1 task 1 practical gr12

The document provides instructions for Grade 12 learners on how to complete a practical assessment in Life Sciences, focusing on DNA to protein synthesis. It outlines the requirements for submission, including formatting, legibility, and the use of specific resources. The assessment consists of transcription and translation tasks, mutation analysis, and questions on the concepts of transcription and translation.

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3K views9 pages

life science term 1 task 1 practical gr12

The document provides instructions for Grade 12 learners on how to complete a practical assessment in Life Sciences, focusing on DNA to protein synthesis. It outlines the requirements for submission, including formatting, legibility, and the use of specific resources. The assessment consists of transcription and translation tasks, mutation analysis, and questions on the concepts of transcription and translation.

Uploaded by

no onee
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Learner instructions

1. The following assessments may be typed or handwritten unless stated otherwise in


the assessment instructions.
2. If handwritten, write neatly and legibly in blue ink and use the TDA Answer Book.
3. Write your name and surname on each page.
4. Number each page.
5. Submit as a SINGLE PDF document unless stated otherwise in the assessment
instructions.
6. Make sure it is submitted in the correct page order and all pages are upright.
7. It is the responsibility of the learner to make sure the upload was correct and
successful.

Leerder instruksies

1. Die volgende assessering mag getik of handgeskrewe wees tensy daar anders
aangedui word in die assesseringinstruksies.
2. Indien jy skryf, skryf asseblief netjies en leesbaar in blou ink en gebruik die TDA
Antwoordboek.
3. Skryf jou naam en van op elke bladsy.
4. Nommer elke bladsy.
5. Handig in as ‘n ENKELE PDF dokument tensy daar anders aangedui word in die
assesseringsinstruksies.
6. Maak seker dat die bladsye in die korrekte volgorde en regop opgelaai word.
7. Dit is die verantwoordelikheid van die leerder om seker te maak dat die inhandiging
reg en suksesvol is.

Do not rely on artificial intelligence (AI) to do your work for you. Doing so will contravene
Think Digital’s Academic Assessment Policy and penalties will apply.
LIFE SCIENCES

GRADE 12

TERM 1

TASK 1 – PRACTICAL
Total : 30

Time allocation : 60 Minutes

Submission date : February 2025

Examiner : R du Toit

Moderator : J Joubert
Gr12 Life Sciences Task 1 Term 1 – 2025 @TAC
Practical

Instructions and information

1. Make use of a study guide, textbook or any other relevant resource materials
with information on DNA and protein synthesis to complete this task.

2. This task must be completed under supervision within the given time
allocation.

3. Make use of the given answer sheets.

4. Write your name and surname in the given space.

5. Write neatly and legible.

Developed by That Assessment Company 2


Gr12 Life Sciences Task 1 Term 1 – 2025 @TAC
Practical

DNA to Protein synthesis

Objective: To learn how DNA is used to make proteins through the processes of
transcription and translation.

Materials needed: DNA sequence cards (normal and mutated)


mRNA codon chart (showing how codons match to amino acids)

Above-mentioned information will be provided on the worksheet.

Developed by That Assessment Company 3


Gr12 Life Sciences Task 1 Term 1 – 2025 @TAC
Practical

Name and Surname

SECTION A: QUESTION 1
TRANSCRIPTION (DNA TO MRNA)

1.1 Transcribe the following DNA sequence to mRNA.


Write the mRNA sequence in the space below each triplet of DNA nucleotides: (6)

TAC ACC TTG GCG ACG ACT

Make use of the following rules when answering the above question:
A (Adenine) pairs with U (Uracil) and T (Thymine) pairs with A (Adenine).
C (Cytosine) pairs with G (Guanine) and G (Guanine) pairs with C (Cytosine).

A–U
T–A
C–G
G–C
[6]

Developed by That Assessment Company 4


Gr12 Life Sciences Task 1 Term 1 – 2025 @TAC
Practical

SECTION B: QUESTION 2
TRANSLATION (MRNA TO PROTEIN)

2.1 Identify the mRNA codons from Question 1 on the following codon chart and
break them into groups of three bases (codons). Determine which amino acid
each of the mRNA represent.

Record the amino acids in the space provided in the following table:

mRNA

Amino
acid

[6]

Developed by That Assessment Company 5


Gr12 Life Sciences Task 1 Term 1 – 2025 @TAC
Practical

SECTION C: QUESTION 3
MUTATIONS AND THEIR EFFECTS:

What is a mutation?
A Change in the DNA sequence by means of substitution, insertion or deletion.

The following example is a mutated DNA sequence:

TAC ATC TTG GCG ACG ACT

3.1 One base is changed. Transcribe the mutated DNA to mRNA. Fill in the
above table by writing the mRNA in the space provided with each triplet of
mutated DNA and indicate the mutated letter. (2)

3.2 Translate the mutated mRNA by finding the new codons on the chart and
briefly explain the change in the amino acid sequence.
(3)
Compare the new amino acid sequence with the original one and study the difference.
Think about how it might possibly affect the protein that is formed.
[5]

Developed by That Assessment Company 6


Gr12 Life Sciences Task 1 Term 1 – 2025 @TAC
Practical

SECTION D: QUESTION 4

Complete the worksheet:

4.1 What is transcription? (5)


………………………………………………………………………………………
………………………………………………………………………………………
………………………………………………………………………………………
………………………………………………………………………………………
………………………………………………………………………………………

4.2 What is translation? (2)


………………………………………………………………………………………
………………………………………………………………………………………
………………………………………………………………………………………

4.3 What was the amino acid sequence for the normal DNA? (2)
……………………………………………………………………………………….
……………………………………………………………………………………….

4.4 What was the amino acid sequence after mutation? (2)
……………………………………………………………………………………….
……………………………………………………………………………………….

Developed by That Assessment Company 7


Gr12 Life Sciences Task 1 Term 1 – 2025 @TAC
Practical

4.5 Which gene mutation took place and briefly describe how the change in the
amino acid sequence might affect the protein formed. (2)
…………………………………………………………………………………………
…………………………………………………………………………………………
[13]

MARK ALLOCATION

Description Maximum mark Learner mark

Transcription from DNA to mRNA 6

Translation from mRNA to protein 6

Transcription from mutated DNA to


mRna 2
Correct change indicated

Translation of mutated mRNA to


3
amino acids

Meaning of Transcription 5

Meaning of Translation 2

Normal DNA sequence 2

Mutated amino acid sequence 2

Gene mutation and how it affects


2
protein

GRAND TOTAL 30

Developed by That Assessment Company 8

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