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Peptide Status Detection

Files:

  • 'create_amylnset.py': Python script used to extract positive data regions and prepare dataset for classification from the protein sequences in fasta format.
  • 'classifier.py': Classifier written in python script using scikit-learn to predict the amyloidogenic regions of size 'n' in a protein sequence.
  • Data: Protein sequences, both positive and negative regions.

Dependancies:

  • Scikit-Learn
  • Numpy
  • Pylab
  • Pandas

Instructions:

  • Make sure that all dependancies are pre-installed
  • Clone the repository as .zip
  • Extract the contents
  • The protein sequence for which the amyloidogenic regions are to be predicted in .fasta format is to be renamed as input.fasta and placed in the 'data' directory.
  • Run the 'classifier.py' script and input the window size.
  • Clean the 'data/temp' directory if required.

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A classifier written in python to attempt to classify n length peptides as amyloidogenic or non-amyloidogenic.

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