Browse free open source Python Bio-Informatics Software and projects below. Use the toggles on the left to filter open source Python Bio-Informatics Software by OS, license, language, programming language, and project status.

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  • 1
    QUAST

    QUAST

    Quality Assessment Tool for Genome Assemblies

    QUAST performs fast and convenient quality evaluation and comparison of genome assemblies. It is maintained by the Gurevich lab at HIPS (https://helmholtz-hips.de/en/hmsb). For the most up-to-date description, please visit http://quast.sf.net. Below are just some highlights. QUAST computes several well-known metrics, including contig accuracy, the number of genes discovered, N50, and others, as well as introducing new ones, like NA50 (see details in the paper and manual). A comprehensive analysis results in summary tables (in plain text, tab-separated, and LaTeX formats) and colorful plots. The tool also produces web-based reports condensing all information in one easy-to-navigate file. QUAST and its three follow-up papers (MetaQUAST, Icarus, QUAST-LG) papers were published in Bioinformatics; the last paper (WebQUAST) is out in Nucl Acid Research.
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    Downloads: 72 This Week
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  • 2
    The Sashimi project hosts the Trans-Proteomic Pipeline (TPP), a mature suite of tools for mass-spec (MS, MS/MS) based proteomics: statistical validation, quantitation, visualization, and converters from raw MS data to the open mzML/mzXML formats.
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    Downloads: 37 This Week
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  • 3

    miRge3

    Comprehensive analysis of small RNA sequencing data

    An update to Python package to perform comprehensive analysis of small RNA sequencing data, including miRNA annotation, A-to-I editing, novel miRNA detection, isomiR analysis, visualization through IGV, processing Unique Molecular Identifieres (UMI), tRF detection and producing interactive graphical output. miRge3.0 is developed in python v3.8 and is a recent update of our previous version miRge2.0. This build includes command line interface (CLI) and cross-platform Graphical User Interface (GUI). For more details refer to documentation link below.
    Downloads: 31 This Week
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  • 4
    BoulderALE is an RNA alignment editor, which allows for the annotation of basepairs, annotation and collapsing of features (horizontal) and sequences (vertical), along with 2D display of sequences and base composition given a secondary structure.
    Downloads: 0 This Week
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  • 5
    CellPublisher is a free, open source program to improve the navigation of biological pathways. It converts CellDesigner diagrams into fully-featured maps that live inside a browser. The navigation is based on the Google maps API.
    Downloads: 0 This Week
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  • 6
    CircularLogo is a light-weighted, easy to use web application that visualizes the intra-motif dependencies of a DNA or RNA motif.
    Downloads: 0 This Week
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  • 7

    GCB_package

    Stand-alone version of the Genome Complexity Browser

    This application allows observing genome rearrangements in prokaryotic genomes. It provides rearrangements frequencies profiles and genomes graph representation.
    Downloads: 0 This Week
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  • 8
    GIIAF Microscopy Library

    GIIAF Microscopy Library

    The GIIAF Microscopy Library, that uses customised OMERO software

    This project incorporates a suite of tools that aim to allow researchers within Griffith's Imaging and Image Analysis Facility (GIIAF) to efficiently and effectively provide secure, centralised, web-accessible data storage, management and manipulation. The open-source Java-based OMERO software was customised to provide most of the features of this project.
    Downloads: 0 This Week
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  • 9

    GenEpiO

    The Genomic Epidemiology Ontology covers food-borne disease terms

    Here we introduce a Genomic Epidemiology Ontology (GenEpiO) that covers vocabulary necessary to identify, document and research food-borne pathogens and associated outbreaks. We envision various subdomains including genomic laboratory testing, specimen and isolate metadata, and epidemiological case investigations. The project files are currently hosted at https://github.com/GenEpiO/genepio/ . Here we provide the genepio-consortium@lists.sourceforge.net listserve. Terms for these subdomains have partially been implemented in the main file, **genepio.owl**, which imports terms from over 25 OboFoundry.org ontologies. Also we have added a number of terms that so far haven't been covered via OboFoundry. Recognizing that GenEpiO encompasses many domains, we are advocating a consortium approach for enhancing its content via interested parties that need particular domain terminology.
    Downloads: 0 This Week
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  • 10
    This Project moved to https://sourceforge.net/projects/synbiowave/ because the name GeneWave is a registered trademark... Please do not use this project anymore.
    Downloads: 0 This Week
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  • 11
    Pathomx

    Pathomx

    Workflow-based data analysis built on IPython

    Pathomx is a workflow-based tool for the analysis and visualisation of experimental data. Initially created as a tool for metabolomic data analysis is has been extended and can now be used for any scientific and non-scientific data analysis.
    Downloads: 0 This Week
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  • 12
    PhyloTrack

    PhyloTrack

    PhyloTrack, D3.js and JBrowse for phylogeny and positioning of samples

    PhyloTrack is a JavaScript--based software tool that integrates the D3.js library for data visualization with the JBrowse tool for genome browser representation. It requires a phylogenetic tree of the common Newick data format as input, as well as three meta data files for samples, clade-defining nodes and clade color definitions - all in tab delimited format. Functionality within PhyloTrack shows the informative markers at each node in the phylogenetic tree, therefore highlighting clade-defining polymorphism. This functionality has been implemented using the tabix tool on the server side, providing simple and rapid access to the information at each tree node, including informative SNPs stored in VCF-similar files. These informative variants have been established by comparing allele frequencies between strain-types using ancestral node comparisons and FST measures of population differentiation.
    Downloads: 0 This Week
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  • 13

    WebChemViewer

    A simple program for sharing molecular structures with associated data

    Sharing lists of molecular structures with associated chemical properties is a common task in computer-aided drug design and medicinal chemistry. WebChem Viewer is a simple, free, open-source program that generates HTML-formatted output that can be viewed in any modern web browser, on any operating system (including mobile), without requiring the installation of additional software. The output can also be easily incorporated into existing web pages. WebChem Viewer is released under the FreeBSD license. It was created by Jacob Durrant, a post-doc in the lab of Rommie E. Amaro.
    Downloads: 0 This Week
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  • 14
    Ymap - Yeast Mapping Analysis Pipeline

    Ymap - Yeast Mapping Analysis Pipeline

    Pipeline for large-scale genome changes analysis of genome datasets.

    The active use repository has migrated over to: https://github.com/darrenabbey/ymap The repository here was errantly created with some large binary files included. Attempts to extract the files from the history here have failed. A copy of the history was successfully scrubbed and then hosted at github. -------- Eukaryotic pathogens have complicated and dynamic genomes. To facilitate analysis of copy number variations (CNV), single nucleotide polymorphisms (SNPs), and loss of heterozygosity (LOH) events in Candida albicans, the most common human fungal pathogen, we developed a pipeline for analyzing diverse genome-scale datasets from microarray, deep sequencing, and restriction site associated DNA sequence experiments for clinical and laboratory strains. The YMAP pipeline automatically illustrates genome-wide information in a single intuitive figure and is readily modified for the analysis of other categories of data and other pathogen species with small genomes.
    Downloads: 0 This Week
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  • 15
    bioweb

    bioweb

    polyglot language framework to analyze genetic data

    polyglot framework using Python/C++/JavaScript to fast develop applications to analyze biological sequences
    Downloads: 0 This Week
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  • 16

    epidaurus

    tumor epigenetic database

    Epidaurus is a collection of epigenetic datasets including transcription factor ChIP-seq, histone ChIP-seq, DNase-seq, FAIRE-seq, DNA methylation, etc. It also includes commonly used genome features (GC content, conservation) and RNA-seq. A user friendly interface has been developed to interrogate and visuzlize these datasets.
    Downloads: 0 This Week
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    Downloads: 0 This Week
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  • 18

    openSEQ

    NGS compute distro proloaded with pipeline analysis software

    Forked Ubuntu 14.04 minimal install with XOrg and FluxBox desktop environment for web-based pipeline construction and job submission. HOWTO: 1) Set VM network settings to a bridged adapter type. 2) Load VM to client 3) From host: $ ssh -X ubuntu@<foobar> 'firefox && butterfly.server.py --unsecure' --- passwd = 616287xx 5) or ssh into host with X forwarding, and type runme This will launch an X-session of Firefox on the client, which will then be forwarded to the host. The first homepage tab links to our pipeline constructer. The second homepage tab links to a xterm session on the client. Software included (location - name): path - biobambam path - bwa path - bowtie2 path - bowtie path - cufflinks path - bcftools path - tophat path - scalpel path - samtools path - sra-toolkit path - bamtools path - delly path - delly-parallel path - picard-tools path - fastahack path - twoBitToFa ~/prog/java/ - mutect ~/prog/python/ - platypus ~/prog/java/ - gatk
    Downloads: 0 This Week
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  • 19
    pyMantis
    pyMantis is a data-management system for (systems) biology build on the web2py framework. It features: tree based file explorer, relational db table wizzard with automated creation of user interfaces, internal and external access management, wiki, ..
    Downloads: 0 This Week
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  • 20
    rxncon
    The complexity of cellular networks is an outstanding challenge for documentation, visualisation and mathematical modelling. In this project, we develop a new way to describe these networks that minimises the combinatorial complexity and allows an automatic visualisation and export of mathematical (ODE/rulebased) models.
    Downloads: 0 This Week
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