Compare the Top HPC Software for Startups as of June 2025

What is HPC Software for Startups?

High-Performance Computing (HPC) software are applications designed to maximize computational power, enabling complex and resource-intensive tasks to be executed efficiently. These programs optimize parallel processing, often leveraging supercomputers or distributed computing clusters to solve problems in fields like scientific research, engineering, and data analytics. HPC software includes components for workload management, data communication, and performance tuning, ensuring scalability and efficient resource utilization. Examples include simulation software, machine learning frameworks, and tools for weather modeling or molecular dynamics. By harnessing advanced algorithms and hardware, HPC software accelerates computation, reducing the time required for tasks that would otherwise take weeks or months on conventional systems. Compare and read user reviews of the best HPC software for Startups currently available using the table below. This list is updated regularly.

  • 1
    Samadii Multiphysics

    Samadii Multiphysics

    Metariver Technology Co.,Ltd

    Metariver Technology Co., Ltd. is developing innovative and creative computer-aided engineering (CAE) analysis S/W based on the latest HPC technology and S/W technology including CUDA technology. We will change the paradigm of CAE technology by applying particle-based CAE technology and high-speed computation technology using GPUs to CAE analysis software. Here is an introduction to our products. 1. Samadii-DEM (the discrete element method): works with the discrete element method and solid particles. 2. Samadii-SCIV (Statistical Contact In Vacuum): working with high vacuum system gas-flow simulation. Using Monte Carlo simulation. 3. Samadii-EM (Electromagnetics): For full-field interpretation 4. Samadii-Plasma: Plasma simulation for Analysis of ion and electron behavior in an electromagnetic field. 5. Vampire (Virtual Additive Manufacturing System): Specializes in transient heat transfer analysis. additive manufacturing and 3D printing simulation software
  • 2
    Azure CycleCloud
    Create, manage, operate, and optimize HPC and big compute clusters of any scale. Deploy full clusters and other resources, including scheduler, compute VMs, storage, networking, and cache. Customize and optimize clusters through advanced policy and governance features, including cost controls, Active Directory integration, monitoring, and reporting. Use your current job scheduler and applications without modification. Give admins full control over which users can run jobs, as well as where and at what cost. Take advantage of built-in autoscaling and battle-tested reference architectures for a wide range of HPC workloads and industries. CycleCloud supports any job scheduler or software stack—from proprietary in-house to open-source, third-party, and commercial applications. Your resource demands evolve over time, and your cluster should, too. With scheduler-aware autoscaling, you can fit your resources to your workload.
    Starting Price: $0.01 per hour
  • 3
    Lustre

    Lustre

    OpenSFS and EOFS

    The Lustre file system is an open-source, parallel file system that supports many requirements of leadership class HPC simulation environments. Whether you’re a member of our diverse development community or considering the Lustre file system as a parallel file system solution, these pages offer a wealth of resources and support to meet your needs. The Lustre file system provides a POSIX-compliant file system interface, which can scale to thousands of clients, petabytes of storage, and hundreds of gigabytes per second of I/O bandwidth. The key components of the Lustre file system are the Metadata Servers (MDS), the Metadata Targets (MDT), Object Storage Servers (OSS), Object Server Targets (OST), and the Lustre clients. Lustre is purpose-built to provide a coherent, global POSIX-compliant namespace for very large-scale computer infrastructure, including the world's largest supercomputer platforms. It can support hundreds of petabytes of data storage.
    Starting Price: Free
  • 4
    NVIDIA GPU-Optimized AMI
    The NVIDIA GPU-Optimized AMI is a virtual machine image for accelerating your GPU accelerated Machine Learning, Deep Learning, Data Science and HPC workloads. Using this AMI, you can spin up a GPU-accelerated EC2 VM instance in minutes with a pre-installed Ubuntu OS, GPU driver, Docker and NVIDIA container toolkit. This AMI provides easy access to NVIDIA's NGC Catalog, a hub for GPU-optimized software, for pulling & running performance-tuned, tested, and NVIDIA certified docker containers. The NGC catalog provides free access to containerized AI, Data Science, and HPC applications, pre-trained models, AI SDKs and other resources to enable data scientists, developers, and researchers to focus on building and deploying solutions. This GPU-optimized AMI is free with an option to purchase enterprise support offered through NVIDIA AI Enterprise. For how to get support for this AMI, scroll down to 'Support Information'
    Starting Price: $3.06 per hour
  • 5
    Ansys HPC
    With the Ansys HPC software suite, you can use today’s multicore computers to perform more simulations in less time. These simulations can be bigger, more complex and more accurate than ever using high-performance computing (HPC). The various Ansys HPC licensing options let you scale to whatever computational level of simulation you require, from single-user or small user group options for entry-level parallel processing up to virtually unlimited parallel capacity. For large user groups, Ansys facilitates highly scalable, multiple parallel processing simulations for the most challenging projects when needed. Apart from parallel computing, Ansys also offers solutions for parametric computing, which enables you to more fully explore the design parameters (size, weight, shape, materials, mechanical properties, etc.) of your product early in the development process.
  • 6
    Intel oneAPI HPC Toolkit
    High-performance computing (HPC) is at the core of AI, machine learning, and deep learning applications. The Intel® oneAPI HPC Toolkit (HPC Kit) delivers what developers need to build, analyze, optimize, and scale HPC applications with the latest techniques in vectorization, multithreading, multi-node parallelization, and memory optimization. This toolkit is an add-on to the Intel® oneAPI Base Toolkit, which is required for full functionality. It also includes access to the Intel® Distribution for Python*, the Intel® oneAPI DPC++/C++ C¿compiler, powerful data-centric libraries, and advanced analysis tools. Get what you need to build, test, and optimize your oneAPI projects for free. With an Intel® Developer Cloud account, you get 120 days of access to the latest Intel® hardware, CPUs, GPUs, FPGAs, and Intel oneAPI tools and frameworks. No software downloads. No configuration steps, and no installations.
  • 7
    Intel Quartus Prime Design
    Intel offers a comprehensive suite of development tools tailored for designing with Altera FPGAs, CPLDs, and SoC FPGAs, catering to hardware engineers, software developers, and system architects. The Quartus Prime Design Software serves as a multiplatform environment encompassing all necessary features for FPGA, SoC FPGA, and CPLD design, including synthesis, optimization, verification, and simulation. For high-level design, Intel provides tools such as the Altera FPGA Add-on for oneAPI Base Toolkit, DSP Builder, High-Level Synthesis (HLS) Compiler, and the P4 Suite for FPGA, facilitating efficient development in areas like digital signal processing and high-level synthesis. Embedded developers can utilize the Nios V soft embedded processors and a range of embedded design tools, including the Ashling RiscFree IDE and Arm Development Studio (DS) for Altera SoC FPGAs, to streamline software development for embedded systems.
  • 8
    PowerFLOW

    PowerFLOW

    Dassault Systèmes

    By leveraging our unique, inherently transient Lattice Boltzmann-based physics PowerFLOW CFD solution performs simulations that accurately predict real world conditions. Using the PowerFLOW suite, engineers evaluate product performance early in the design process prior to any prototype being built — when the impact of change is most significant for design and budgets. PowerFLOW imports fully complex model geometry and accurately and efficiently performs aerodynamic, aeroacoustic and thermal management simulations. Automated domain discretization and turbulence modeling with wall treatment eliminates the need for manual volume meshing and boundary layer meshing. Confidently run PowerFLOW simulations using large number of compute cores on common High Performance Computing (HPC) platforms.
  • 9
    NVIDIA NGC
    NVIDIA GPU Cloud (NGC) is a GPU-accelerated cloud platform optimized for deep learning and scientific computing. NGC manages a catalog of fully integrated and optimized deep learning framework containers that take full advantage of NVIDIA GPUs in both single GPU and multi-GPU configurations. NVIDIA train, adapt, and optimize (TAO) is an AI-model-adaptation platform that simplifies and accelerates the creation of enterprise AI applications and services. By fine-tuning pre-trained models with custom data through a UI-based, guided workflow, enterprises can produce highly accurate models in hours rather than months, eliminating the need for large training runs and deep AI expertise. Looking to get started with containers and models on NGC? This is the place to start. Private Registries from NGC allow you to secure, manage, and deploy your own assets to accelerate your journey to AI.
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