Best Microsegmentation Software

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Compare the Top Microsegmentation Software as of October 2025

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What is Microsegmentation Software?

Microsegmentation software is a data security solution that can be used to protect applications and data in cloud environments. It provides visibility into the network traffic within an organization, allowing users to set and enforce segmentation policies as needed. By creating micro-segments within the larger network environment, it helps to ensure that potential breaches are contained with minimum disruption. The software uses both analytics and automation to enforce these policies, helping to reduce the burden of manual tasks for IT teams. Finally, advanced features such as encryption and IDS/IPS help further protect an organization from threats and malicious actors. Compare and read user reviews of the best Microsegmentation software currently available using the table below. This list is updated regularly.

  • 1
    Prisma Cloud

    Prisma Cloud

    Palo Alto Networks

    Comprehensive cloud native security. Prisma™ Cloud delivers comprehensive security across the development lifecycle on any cloud, enabling you to develop cloud native applications with confidence. The move to the cloud has changed all aspects of the application development lifecycle – security being foremost among them. Security and DevOps teams face a growing number of entities to secure as the organization adopts cloud native approaches. Ever-changing environments challenge developers to build and deploy at a frantic pace, while security teams remain responsible for the protection and compliance of the entire lifecycle. Firsthand accounts of Prisma Cloud’s best-in-class cloud security capabilities from some of our satisfied customers.
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  • 2
    Illumio

    Illumio

    Illumio

    Stop ransomware. Isolate cyberattacks. Segment across any cloud, data center, or endpoint in minutes. Accelerate your Zero Trust journey and protect your organization with automated security enforcement, intelligent visibility, and unprecedented scale. Illumio Core stops attacks and ransomware from spreading with intelligent visibility and micro-segmentation. Get a map of workload communications, quickly build policy, and automate enforcement with micro-segmentation that is easy to deploy across any application, cloud, container, data center, and endpoint. Illumio Edge extends Zero Trust to the edge to contain malware and ransomware to a single laptop instead of thousands. Turn laptops into Zero Trust endpoints, contain an infection to a single machine, and give endpoint security tools like EDR more time to detect and responds to threats.
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