Y'ALL THIS IS SO COOL AND COULD BE HUGE FOR SO MANY PEOPLE

additional article:

BRIEF SUMMARY:

It is an mRNA vaccine with successful mammalian (mice) trials.

The vaccine targets life-threatening inflammation and immune responses.

Mice with serious allergies, which received the vaccine tailored to those allergies, stopped having immune reactions when exposed to those allergens.

Aka: vaccinating against allergies.

If they can develop it for safe human use, it could save an enormous amount of lives, and IMPROVE the lives of people who live in constant fear of encountering their lethal allergens.

Because it’s able to be tailored, and specifically affects the immune system response, it may one day be able to adjust immune responses to chronic conditions like Celiac Disease, Asthma, Food Sensitivities, Food Allergies, and potentially many other autoimmune disorders.

Imagine a future where a child with a deadly shellfish allergy could get a shot and just… not be allergic anymore. Eat shrimp with no fear.

Be born with Celiac, get a shot, and casually eat gluten with no side effects.

We’re not quite there yet, but it’s performing well in mammalian trials, and we have high hopes!

"these researchers published a paper on something that literally any of us could have told you 🙄" ok well my supervisors wont let me write something in my thesis unless I can back it up with a citation so maybe it's a good thing that they're amplifying your voice to the scientific community in a way that prevents people from writing off your experiences as annecdotal evidence

they did the research in the first place because they believed you and wanted to tell people about it. they are not our enemies.

The bird app has a lot of garbage but this thread really tickled me this morning:

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ftr I am forever going to be bitter that the post I wanted to be "let's talk about extinct ecosystems and how cool they are!" got derailed into yet another post just talking about a single taxon like the millions of other posts on palaeoblr

Please tell me more about these extinct ecosystems. Why did they go extinct? Could an ecosystem like that return?

When I say "extinct ecosystem", I mean those ecosystems that have existed in the past, with extinct animals and plants etc. inhabiting them

by their very definition, they are gone forever

there are ones that were truly unique, like Polar Tropical Forests and Fern Prairies, that we just could not have today

but there were ones that have equivalents to today, as well, like the first savannahs and steppes of the Miocene - they just have earlier versions of the plants and animals

there were so many because there are so many today, and each one had its own flora and fauna and was glorious

There's the wetlands and forests of Hell Creek in the Latest Cretaceous

the bizarre Volcanic Lake Forests of the Jehol Biota

whatever the hell the Ediacaran Reefs were

the Scale Tree Swamp Forests of the Carboniferous

"Mesozoic 2" aka pre-human Aotearoa

the Western Interior Seaway dominated by Mosasaurs

and so many other things, I couldn't possibly list them all. Every time period had its own biosphere and biomes, and they were all unique.

#i wanna see the Aurora Borealis over a tropical forest#BC Canada has a Boreal Rainforest so you can definitely get that

that isn't what I mean by "Polar Tropical Forest"

I mean a tropical forest

at the poles

ie, the ecosystems present during the Paleocene-Eocene Thermal Maximum

we have fossils of plants that showcase how different tropical plant lifestyles had to be up at the poles because of the light weirdness

the important part is "tropical", not "wet/rainforest". those are two different things

Temperate and Boreal Rainforests are wonderful and some of my favorite living biomes, but they aren't what I was talking about

May I ask about the fern prairies? That sounds really cool!

Grass is a relatively recent thing

it first evolved in the latest Cretaceous, but it didn't actually take over everywhere until the Miocene, when grasses that process light differently (look up C3 vs C4 photosynthesis) evolved and just took the fuck over the planet

before then, other plants formed the low ground cover over the earth, and in many places those plants were ferns - spread all over the ground and covering it, much like grass, but significantly less dense. Dirt would have been much more common everywhere.

This is why I am begging every single game developer to remember that grass is not a neutral ground cover

My favorite extinct ecosystem, if it counts while being as physically tiny as it was, is the floating logs that existed in the ocean between the first appearance of woody trees and the first appearance of organisms that could break down wood - floating reefs of a sort, trailing enormous filter-feeding crinoids below them. The baleen whales of their time

yeah that counts! And how bizarre those must have been!!!

Speaking of reefs, we're so used to rocky or coral reefs in the moderns world but there have been so many different reefs throughout prehistory that were made of things that straight up don't exist any more!

Like the reefs of the late Devonian, which were made of stromatoporoids, which may have resembled corals but were actually a highly diverse extinct group of sponges!

This is one of my own reconstructions of a stromatoporoid reef off the coast of Devonian Australia (plus anachronistic underwater baited camera):

The Cretaceous also had some wild extinct reefs which are known as carbonate reefs and were dominated by a group of bivalve molluscs called rudists!

Scale tree swamps are the only one of these I know anything about and they were SO WEIRD. There's definitely some controversy about how they functioned cause these things are hard to work out from fossils, but the current thinking is that these trees shot up to around 100 feet tall in 10-15 years, grew more tightly packed together than basically any modern forest, produced spores one time and then promptly keeled over and died. Forests just do not work like this anymore! It's not just different types of trees, it's a whole *different type of forest* that has gone extinct! Different nutrient cycling, different natural rhythms, different everything!

Even today there are all kinds of niche hyperlocal ecosystems that function in their own distinct ways - shale barrens, waxcap grasslands, cataract bogs. What else have we just never seen??

Anxiety over all the prehistoric organisms we’ll never know, meet your big sibling: anxiety over all the prehistoric ECOSYSTEMS we’ll never know

Pretty incredible news to hear during tough times

Source.

what annoys me about explaining evolution to people who don’t think it’s real is that everyone’s idea of how it works seems to be from this

Whereas the reality is far more like

Was not expecting this many of you to resonate with Millennium Death Plinko

It’s crazy that countries on the edge of the Sahara desert are reversing desertification by just digging half circles

The ground in these places is too compact for water to soak in during wet season which leads to flooding but digging these holes gives the water a place to stop and soak in. And they’re pushing back the desert with this. By just digging holes.

The new plants also help even more water soak into the ground which reduces flooding even more.

These places also give people places to grow food and graze animals like people are turning completely dry compact desert into a refuge for wildlife and plants and solving regional food insecurity just by digging holes.